ABCA13 and APOA2

Number of citations of the paper that reports this interaction (PubMedID 11162594)
88

Data Source:
BioGRID (pull down)

		ABCA13	APOA2
Description		ATP binding cassette subfamily A member 13	apolipoprotein A2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Secretory Granule Membrane Azurophil Granule Membrane Intracellular Membrane-bounded Organelle Intracellular Vesicle	Extracellular Region Early Endosome Endoplasmic Reticulum Lumen Cytosol Very-low-density Lipoprotein Particle High-density Lipoprotein Particle Spherical High-density Lipoprotein Particle Chylomicron Extracellular Exosome Blood Microparticle
	Molecular Function	Lipid Transporter Activity ATP Binding ATPase-coupled Transmembrane Transporter Activity ABC-type Transporter Activity	Signaling Receptor Binding Lipid Transporter Activity Protein Binding Phospholipid Binding High-density Lipoprotein Particle Binding Lipid Binding Cholesterol Binding Heat Shock Protein Binding Phosphatidylcholine Binding Apolipoprotein Receptor Binding Protein Homodimerization Activity Protein Heterodimerization Activity Lipase Inhibitor Activity Phosphatidylcholine-sterol O-acyltransferase Activator Activity High-density Lipoprotein Particle Receptor Binding Cholesterol Transfer Activity
	Biological Process	Lipid Transport Positive Regulation Of Cholesterol Transport Ceramide Transport Transmembrane Transport Positive Regulation Of Synaptic Vesicle Endocytosis	Acute Inflammatory Response Negative Regulation Of Cytokine Production Involved In Immune Response Triglyceride Metabolic Process Phosphatidylcholine Biosynthetic Process Cholesterol Metabolic Process Phospholipid Catabolic Process Response To Xenobiotic Stimulus Response To Glucose Positive Regulation Of Cholesterol Esterification Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling Protein Oxidation Peptidyl-methionine Modification Regulation Of Intestinal Cholesterol Absorption Cholesterol Transport Animal Organ Regeneration Regulation Of Protein Stability Negative Regulation Of Cholesterol Transport Positive Regulation Of Interleukin-8 Production Cholesterol Efflux Phospholipid Efflux Triglyceride-rich Lipoprotein Particle Remodeling Low-density Lipoprotein Particle Remodeling High-density Lipoprotein Particle Remodeling High-density Lipoprotein Particle Assembly High-density Lipoprotein Particle Clearance Lipoprotein Metabolic Process Cholesterol Homeostasis Response To Estrogen Reverse Cholesterol Transport Diacylglycerol Catabolic Process Positive Regulation Of Phagocytosis Protein Stabilization Negative Regulation Of Lipid Catabolic Process Positive Regulation Of Lipid Catabolic Process Response To Glucocorticoid Negative Regulation Of Lipase Activity Negative Regulation Of Cholesterol Import Negative Regulation Of Cholesterol Transporter Activity Intermembrane Lipid Transfer
Pathways		Neutrophil degranulation	PPARA activates gene expression Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation Chylomicron assembly Chylomicron remodeling Retinoid metabolism and transport Retinoid metabolism and transport
Drugs			Zinc Copper Zinc acetate
Diseases
GWAS		Cerebrospinal fluid clusterin levels ( 26545630) Gut microbiota (bacterial taxa) ( 27723756) QT interval (ambient particulate matter interaction) ( 28749367) Refractive astigmatism ( 25367360) Vein graft stenosis in coronary artery bypass grafting ( 25881214)
Interacting Genes		4 interacting genes: APOA1 APOA2 CLK1 PKD1L1	30 interacting genes: ABCA13 APOC1 APOD APOF AQP6 C4A CATSPER1 CIAO2A CREB3 CYBC1 GET1 GJA8 HSD17B13 KIR2DL3 LMNA MUC1 NAXE NDRG1 PANX1 PDZK1IP1 PLTP PSCA SCARB1 SLC7A1 SSMEM1 STOM TMEM45A TMEM82 TREM2 VKORC1
Entrez ID		154664	336
HPRD ID		07422	00129
Ensembl ID		ENSG00000179869	ENSG00000158874
Uniprot IDs		A0A0A0MT16 Q86UQ4	P02652
PDB IDs
Enriched GO Terms of Interacting Partners?
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