ARL6IP6 and TBXA2R

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ARL6IP6	TBXA2R
Description		ADP ribosylation factor like GTPase 6 interacting protein 6	thromboxane A2 receptor
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Inner Membrane Integral Component Of Membrane	Acrosomal Vesicle Plasma Membrane Integral Component Of Plasma Membrane Nuclear Speck
	Molecular Function	Protein Binding	Thromboxane A2 Receptor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process		Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Nutrient Response To Xenobiotic Stimulus Second-messenger-mediated Signaling Positive Regulation Of Blood Coagulation Response To Testosterone Thromboxane A2 Signaling Pathway Response To Ethanol Positive Regulation Of Angiogenesis Positive Regulation Of Blood Pressure Positive Regulation Of Vasoconstriction Positive Regulation Of Smooth Muscle Contraction Regulation Of Catalytic Activity Cellular Response To Lipopolysaccharide Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Pathways			Prostanoid ligand receptors G alpha (q) signalling events G alpha (12/13) signalling events Thromboxane signalling through TP receptor
Drugs			Ridogrel Seratrodast Morniflumate
Diseases
GWAS		Lung cancer ( 28604730) Pancreatic cancer ( 29422604) Recurrent major depressive disorder x sex interaction ( 34099189) Refractive error ( 32231278)
Interacting Genes		19 interacting genes: APP AQP6 ARL6 CLRN2 CMTM2 DRD2 EBP FMNL2 GJA8 GPR61 MGST3 RBM43 RUSF1 SLC10A1 TBXA2R TIMMDC1 TMEM205 TMEM80 TMEM86B	35 interacting genes: ADIPOR1 ARL6IP6 C5orf46 EMP1 GJB2 GNA11 GNA12 GNA13 GNAI2 GNAQ GNAS GNB1 GNG2 GPRASP1 GRK5 GRK6 MFSD5 MS4A13 NME2 NOX1 PRDX4 PRKCA PSMA7 PSME3 PTGIR RAB11A RACK1 RAF1 RPGRIP1L SLC35B4 SLC41A1 TM4SF4 VRK2 YWHAZ ZDHHC15
Entrez ID		151188	6915
HPRD ID		12485	01768
Ensembl ID		ENSG00000177917	ENSG00000006638
Uniprot IDs		B3KMZ5 Q8N6S5	P21731 Q05C92 Q0VAB0
PDB IDs			1LBN
Enriched GO Terms of Interacting Partners?
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