GLIS1 and SPRR1A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GLIS1	SPRR1A
Description		GLIS family zinc finger 1	small proline rich protein 1A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cornified Envelope Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Epidermis Development Peptide Cross-linking Keratinocyte Differentiation Keratinization
Pathways			Formation of the cornified envelope
Drugs
Diseases
GWAS		Cerebrospinal fluid AB1-42 levels ( 28247064) Digit length ratio ( 29659830) Digit length ratio (left hand) ( 29659830) Digit length ratio (right hand) ( 29659830) Glaucoma (primary open-angle) ( 33627673) Hand grip strength ( 29691431 29313844) Mitral valve prolapse ( 26301497) Monobrow ( 27182965) Nicotine use ( 23942779) Non-substance related behavioral disinhibition ( 23942779) Nose size ( 27182965) Refractive error ( 32231278) Response to statin therapy ( 20339536)	Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		13 interacting genes: ARNT CDK6 CDKN2A GLIS2 LATS2 MYC NFIC RELA SOX3 SPRR1A TCF3 TEAD2 ZDHHC23	3 interacting genes: ACTA1 FCER1G GLIS1
Entrez ID		148979	6698
HPRD ID		13581	01647
Ensembl ID		ENSG00000174332	ENSG00000169474
Uniprot IDs		A0A0D9SEX9 Q8NBF1	P35321
PDB IDs
Enriched GO Terms of Interacting Partners?
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