SAMD11 and ECM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SAMD11	ECM1
Description		sterile alpha motif domain containing 11	extracellular matrix protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Region Extracellular Space Extracellular Matrix Platelet Dense Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Chromatin Binding Protein Binding Histone Binding	Protease Binding Interleukin-2 Receptor Binding Extracellular Matrix Structural Constituent Protein Binding Protein C-terminus Binding Enzyme Binding Laminin Binding
	Biological Process	Negative Regulation Of Transcription, DNA-templated	Ossification Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Negative Regulation Of Cytokine-mediated Signaling Pathway Chondrocyte Development Regulation Of Type 2 Immune Response Endochondral Bone Growth Regulation Of Transcription By RNA Polymerase II Inflammatory Response Signal Transduction Negative Regulation Of Peptidase Activity Regulation Of Bone Mineralization Negative Regulation Of Bone Mineralization Biomineral Tissue Development Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Angiogenesis Regulation Of T Cell Migration
Pathways			Platelet degranulation
Drugs
Diseases
GWAS			Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Migraine ( 27322543) Refractive error ( 32231278) Schizophrenia ( 28991256 30285260) Spontaneous coronary artery dissection ( 32887874 32374345) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		23 interacting genes: BPIFA1 CCHCR1 CT55 ECM1 JMJD7 KRT31 KRT34 KRTAP5-7 NFKBID PLAGL2 PLEKHF2 PRR20A PRR20B PRR20C PRR20D PRR20E REL RTL8C TRAF1 TRAF2 TRIB3 TSC1 ZMYND12	39 interacting genes: A1CF ACTN3 ATN1 BCAS2 BNIP3L C1orf109 CPTP CYSRT1 DDIAS DTX2 ENKD1 FASLG FBLN1 FKBP6 FRS3 FXR1 GCM2 GNE GPANK1 GRN HOXC8 HSPG2 IRAK3 ITGB4 KLHL38 KRTAP5-3 KRTAP9-3 LCE2A LIN7A LMO4 MKRN3 PRKAR2B RERE SAMD11 SGTB SNRPC SRPK1 UBQLN1 UBQLN2
Entrez ID		148398	1893
HPRD ID		10081	03727
Ensembl ID		ENSG00000187634	ENSG00000143369
Uniprot IDs		Q96NU1	A0A140VJI7 Q16610
PDB IDs
Enriched GO Terms of Interacting Partners?
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