ZNF420 and CYP51A1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		ZNF420	CYP51A1
Description		zinc finger protein 420	cytochrome P450 family 51 subfamily A member 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	Monooxygenase Activity Iron Ion Binding Sterol 14-demethylase Activity Oxidoreductase Activity Heme Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Steroid Biosynthetic Process Cholesterol Biosynthetic Process Sterol Metabolic Process Negative Regulation Of Protein Catabolic Process Negative Regulation Of Protein Secretion Demethylation Negative Regulation Of Amyloid-beta Clearance
Pathways		Generic Transcription Pathway TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	Cholesterol biosynthesis Endogenous sterols Activation of gene expression by SREBF (SREBP) EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs			Tioconazole Itraconazole Levoketoconazole (S)-econazole
Diseases
GWAS		Body shape index ( 34021172) Eosinophil percentage of white cells ( 32888494) Hip circumference adjusted for BMI ( 34021172) Plateletcrit ( 32888494) Prudent dietary pattern ( 28644415) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Hippocampal volume in Alzheimer's disease dementia ( 29274321) Lifespan ( 25918517) Pulse pressure ( 30578418)
Interacting Genes		15 interacting genes: C1orf109 CDC42 CDK2AP1 CDKN2A CEP19 CYP4V2 CYP51A1 EXOSC5 HAX1 KRTAP10-7 MDM2 SLC1A7 TNFRSF1B TRIM28 ZNF76	4 interacting genes: GRM3 SHANK3 STT3B ZNF420
Entrez ID		147923	1595
HPRD ID		08122	03381
Ensembl ID		ENSG00000197050	ENSG00000001630
Uniprot IDs		Q8TAQ5	A0A0C4DFL7 Q16850
PDB IDs			3JUS 3JUV 3LD6 4UHI 4UHL 6Q2T 6UEZ
Enriched GO Terms of Interacting Partners?
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