PRR35 and TTLL12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PRR35	TTLL12
Description		proline rich 35	tubulin tyrosine ligase like 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm Microtubule Organizing Center Spindle Midbody
	Molecular Function	Protein Binding	Tubulin-tyrosine Ligase Activity Protein Binding ATP Binding Tubulin Binding Histone-lysine N-methyltransferase Activity H4K20me3 Modified Histone Binding
	Biological Process		Cellular Protein Modification Process Regulation Of Mitotic Cell Cycle Innate Immune Response Negative Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Histone H4-K20 Methylation
Pathways			Carboxyterminal post-translational modifications of tubulin
Drugs
Diseases
GWAS			Molar-incisor hypomineralization ( 23918034) Monocyte count ( 32888494 27863252) Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		80 interacting genes: ABHD11 ACY1 APPL2 ARMC5 ASB15 BEGAIN BIRC7 BPIFA1 C11orf1 C19orf54 CARD10 CCDC136 CNOT2 CRX CYSRT1 EXOC8 FAM168B FHL3 FRYL GIGYF1 GRAP2 HOMER3 HOOK2 HPCA HSPB2 HSPB2-C11orf52 INSC INTS11 JUP KLHL26 KRT31 KRT34 KRT35 KRTAP10-7 KRTAP12-1 KRTAP26-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LASP1 LONRF1 LZTS2 MAGED1 MCCD1 MKRN3 MSS51 MTUS2 N4BP3 NBPF19 NOTCH2NLA OIP5 OXER1 PFDN5 PLAGL2 PPIL1 PPP1R13B PRR20A PRR20B PRR20C PRR20D PRR20E PSTPIP1 RBPMS RNF144B RUSC1 SMUG1 SPAG8 TBX19 TLE5 TRIM27 TRIM54 TRIM73 TTC19 TTLL12 UBASH3B UBXN11 USP54 ZMYND12 ZNF655	7 interacting genes: CSNK2A2 DNAJB1 EEF1A1 EEF1A2 FAM222B PRR35 SUMO2
Entrez ID		146325	23170
HPRD ID		10046	13782
Ensembl ID		ENSG00000161992	ENSG00000100304
Uniprot IDs		P0CG20	A0A024R4U3 Q14166
PDB IDs
Enriched GO Terms of Interacting Partners?
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