CSNK1E and ZNF227

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		CSNK1E	ZNF227
Description		casein kinase 1 epsilon	zinc finger protein 227
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus
	Molecular Function	RNA Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	DNA Repair Protein Phosphorylation Endocytosis Signal Transduction Wnt Signaling Pathway Peptidyl-serine Phosphorylation Negative Regulation Of Protein Binding Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Canonical Wnt Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway Regulation Of Cellular Protein Localization Positive Regulation Of Wnt-mediated Midbrain Dopaminergic Neuron Differentiation Positive Regulation Of Non-canonical Wnt Signaling Pathway	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		WNT mediated activation of DVL Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Circadian Clock Anchoring of the basal body to the plasma membrane Major pathway of rRNA processing in the nucleolus and cytosol AURKA Activation by TPX2	Generic Transcription Pathway
Drugs		Seliciclib
Diseases
GWAS		Keratoconus ( 31855235) Mastocytosis ( 32752121)
Interacting Genes		55 interacting genes: AKAP9 ANKRD6 APC APP ARHGEF1 ARNTL AXIN1 AXIN2 BBS10 BHLHE41 BID CADM4 CLOCK CRY1 CSNK2B DELEC1 DVL1 DVL2 DVL3 ENTR1 FAM110A FAM110C FAM83D FBP1 FBXO7 FBXW11 GTF3C1 HES1 KAT7 MCC NCOA3 NR1D2 PER1 PER2 PER3 PPP1CA PPP1CC PPP1R14A PPP2R5D PPP2R5E PTPRC PTPRD RAD54B RBX1 RORA RORC SOCS3 TAFAZZIN TAOK1 TNS2 TRIM3 WDCP ZMYND8 ZNF227 ZNF618	6 interacting genes: CDKN2A CEP70 CSNK1E GSK3B RPS6KA6 UMPS
Entrez ID		1454	7770
HPRD ID		02919	15752
Ensembl ID		ENSG00000213923	ENSG00000131115
Uniprot IDs		P49674 Q5U045	B7Z6M2 Q658S5 Q86WZ6
PDB IDs		4HNI 4HOK
Enriched GO Terms of Interacting Partners?
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