GSC and FBLN5

		GSC	FBLN5
Description		goosecoid homeobox	fibulin 5
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex	Extracellular Region Extracellular Space Extracellular Matrix Collagen-containing Extracellular Matrix Extracellular Exosome Elastic Fiber
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific RNA Polymerase II-specific DNA-binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	Integrin Binding Calcium Ion Binding Protein Binding Protein C-terminus Binding Extracellular Matrix Constituent Conferring Elasticity Protein Homodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Gastrulation Neural Crest Cell Fate Specification Dorsal/ventral Neural Tube Patterning Signal Transduction Involved In Regulation Of Gene Expression Negative Regulation Of Wnt Signaling Pathway Forebrain Development Middle Ear Morphogenesis Muscle Organ Morphogenesis Embryonic Skeletal System Morphogenesis	Regulation Of Cell Growth Cell-matrix Adhesion Protein Localization To Cell Surface Secretion Elastic Fiber Assembly Regulation Of Removal Of Superoxide Radicals
Pathways			Elastic fibre formation Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs
Diseases
GWAS		Chin dimples ( 27182965) Male-pattern baldness ( 28196072) Nonsyndromic cleft lip with cleft palate ( 28232668) Nose size ( 27182965)	Diastolic blood pressure ( 30578418) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Heel bone mineral density ( 30598549) Height ( 25429064 31562340 18391951) Hip circumference adjusted for BMI ( 34021172) Major depressive disorder ( 34099189) Major depressive disorder x sex interaction ( 34099189) Optic disc size ( 31809533) Pulse pressure ( 27841878 30578418) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		5 interacting genes: FBLN5 FOXA2 SMAD1 SMAD2 SMAD3	23 interacting genes: ATN1 GFI1B GSC HOXA1 LGMN LOXL1 LPA MEOX2 NDUFA4 NUFIP2 OTX1 PAXIP1 PDIA3 PPP2R5C PRNP PSMC1 SERPINA1 SERPINA5 SOD3 ST3GAL3 TOP3B TRIP13 XCL1
Entrez ID		145258	10516
HPRD ID		15928	05204
Ensembl ID		ENSG00000133937	ENSG00000140092
Uniprot IDs		P56915	A0A024R6G3 Q9UBX5
PDB IDs		2DMU
Enriched GO Terms of Interacting Partners?
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