TMEM120B and AQP8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM120B	AQP8
Description		transmembrane protein 120B	aquaporin 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Nuclear Inner Membrane Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Mitochondrial Membrane Apical Part Of Cell
	Molecular Function	Molecular_function Ion Channel Activity Protein Binding	Protein Binding Water Channel Activity
	Biological Process	Biological_process Fat Cell Differentiation Protein Heterooligomerization	Water Transport Transmembrane Transport Cellular Response To CAMP
Pathways			Detoxification of Reactive Oxygen Species Passive transport by Aquaporins
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) HDL cholesterol levels ( 32203549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 24026423 32888494 27863252) Mean reticulocyte volume ( 32888494) Molybdenum levels ( 26025379) Neutrophil count ( 32888494) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494 27863252) White blood cell count ( 32888494)	Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 27400856)
Interacting Genes		58 interacting genes: ALOX5AP ANKS6 APOA5 AQP6 AQP8 BNIP3L CCNDBP1 CD74 COMT CPLX4 CREB3L1 DNAH10 EBP ERGIC3 FCER1G FFAR2 FKBP7 GAD2 GJB1 GORAB GPR152 GPRC5D GPX8 HSD17B11 IFNGR2 IL7R JAGN1 JPH1 KCNJ6 LMNA LRRTM2 MGST3 MRPS18B MTRFR MUC1 NCAPH2 REEP2 REEP4 RETREG3 RNF19B RNF5 SCN3B SH3GL3 SLC10A1 SLC10A6 SLC17A8 SLC18A1 SLC1A3 STOM STX2 TLCD4 TMEM139 TMEM143 TMEM14B TMEM80 TMPRSS2 TMX2 ZDHHC15	6 interacting genes: CYBC1 PLP2 PLPP6 SERP1 STX12 TMEM120B
Entrez ID		144404	343
HPRD ID		19119	04778
Ensembl ID		ENSG00000188735	ENSG00000103375
Uniprot IDs		A0PK00	O94778
PDB IDs
Enriched GO Terms of Interacting Partners?
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