CSF3R and WSB2

Number of citations of the paper that reports this interaction (PubMedID 17001306)
5

Data Source:
BioGRID (affinity chromatography technology, imaging technique, protein complementation assay)

		CSF3R	WSB2
Description		colony stimulating factor 3 receptor	WD repeat and SOCS box containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Endocytic Vesicle Membrane Receptor Complex	Cytosol
	Molecular Function	Cytokine Receptor Activity Protein Binding Cytokine Binding Signaling Receptor Activity Granulocyte Colony-stimulating Factor Binding
	Biological Process	Defense Response Cell Adhesion Signal Transduction Cytokine-mediated Signaling Pathway Neutrophil Chemotaxis Regulation Of Myeloid Cell Differentiation Amelogenesis	Protein Ubiquitination Intracellular Signal Transduction
Pathways		Other interleukin signaling Transcriptional regulation of granulopoiesis Signaling by CSF3 (G-CSF) Signaling by CSF3 (G-CSF) Inactivation of CSF3 (G-CSF) signaling Inactivation of CSF3 (G-CSF) signaling	Neddylation
Drugs		Pegfilgrastim Filgrastim FavId Lenograstim Lipegfilgrastim
Diseases
GWAS		Basophil count ( 32888494) Cerebrospinal fluid p-tau levels ( 29274321) Cerebrospinal fluid t-tau levels ( 29274321) Eosinophil percentage of white cells ( 32888494) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Iron status biomarkers (total iron binding capacity) ( 28334935) Lymphocyte percentage of white cells ( 32888494 27863252) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494 27863252) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 29403010 32888494 27863252)	Chronic rhinosinusitis ( 33393196) Red blood cell count ( 32888494)
Interacting Genes		20 interacting genes: CISH CSF3 ELANE FTH1 GRB2 HCK HPCA INPP5D JAK1 JAK2 LCK LYN PLA2G1B PTPN11 SHC1 SOCS3 STAT3 SYK WSB1 WSB2	4 interacting genes: CSF3R DYNLL1 EZH2 RPN1
Entrez ID		1441	55884
HPRD ID		00737	18305
Ensembl ID		ENSG00000119535	ENSG00000176871
Uniprot IDs		Q99062	Q9NYS7
PDB IDs		1AZ7 2D9Q
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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