CWF19L2 and CALCOCO1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		CWF19L2	CALCOCO1
Description		CWF19 like cell cycle control factor 2	calcium binding and coiled-coil domain 1
Image			No pdb structure
GO Annotations	Cellular Component	Post-mRNA Release Spliceosomal Complex	Nucleus Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Beta-catenin Binding Protein C-terminus Binding Nuclear Receptor Coactivator Activity Sequence-specific DNA Binding Metal Ion Binding Armadillo Repeat Domain Binding
	Biological Process	MRNA Splicing, Via Spliceosome	Signal Transduction Positive Regulation Of Gene Expression Wnt Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Coronary artery disease ( 29212778) Cortex volume ( 31530798) Diastolic blood pressure ( 27841878) Fourth ventricle volume ( 31530798) Parkinson's disease progression (cognitive) ( 33111402) Pars opercularis volume ( 31530798) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)	Panic disorder ( 19165232) Toenail selenium levels ( 25343990) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		80 interacting genes: ABLIM3 APP AXIN2 BACH2 BRCA1 CALCOCO1 CALCOCO2 CARD10 CARD9 CCDC102B CCDC136 CCDC57 CCDC88B CEP63 CEP70 CEP76 CFAP53 CNTROB CWF19L1 DES DISC1 EXOC8 FAM9B FCHO1 FSD2 FXR1 FXR2 GAS8 GFAP GOLGA2 GOLGA6L9 GRIPAP1 HOMER3 HOOK1 HOOK2 HSF2BP IKBKG IKZF1 KANK2 KASH5 KIF24 KIFC3 KRT40 LHX3 LHX9 LIMS1 LMNA LZTS1 LZTS2 M1AP MAD1L1 MEOX1 MTUS2 NAB2 NDEL1 PDE4DIP PIBF1 PICK1 PSTPIP1 RINT1 SF3B4 SNW1 STX11 TAX1BP1 TBC1D1 TFIP11 TP53BP2 TRAF2 TRIM23 TRIM27 TRIM37 TRIM54 TRIM9 VIM VPS52 ZBTB8A ZMYND12 ZNF35 ZNF655 ZRANB1	37 interacting genes: APP APTX ARNT BFSP2 CEP19 CREBBP CRYBA2 CTNNBL1 CWF19L2 CYTH3 DUSP13 ENKD1 EP300 FAM161A FOSL1 FXR1 GABARAPL1 GABARAPL2 GRIK2 IPP ISOC1 KRT15 MAPK1 MYH6 NDC80 NEDD4 PCBD1 POLR2A PRKAA2 RNF8 SH3GL3 SHANK3 SMURF1 SRPK2 TBC1D15 TBC1D17 ZMAT2
Entrez ID		143884	57658
HPRD ID		13102	13868
Ensembl ID		ENSG00000152404	ENSG00000012822
Uniprot IDs		Q2TBE0	A0A024RAZ1 Q9P1Z2
PDB IDs		6ID0 6ID1
Enriched GO Terms of Interacting Partners?
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