ACSM6 and SORCS3

		ACSM6	SORCS3
Description		acyl-CoA synthetase medium chain family member 6	sortilin related VPS10 domain containing receptor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrial Matrix	Membrane Integral Component Of Membrane Glutamatergic Synapse Integral Component Of Postsynaptic Density Membrane
	Molecular Function	Fatty-acyl-CoA Synthase Activity ATP Binding GTP Binding Fatty Acid Ligase Activity Medium-chain Fatty Acid-CoA Ligase Activity Metal Ion Binding Butyrate-CoA Ligase Activity	Protein Binding Neuropeptide Receptor Activity
	Biological Process	Fatty Acid Biosynthetic Process Acyl-CoA Metabolic Process	Neuropeptide Signaling Pathway Learning Memory Regulation Of Long-term Synaptic Depression
Pathways		Beta oxidation of butanoyl-CoA to acetyl-CoA
Drugs
Diseases
GWAS		Low density lipoprotein cholesterol levels ( 33339817) Total cholesterol levels ( 33339817) Triglyceride levels in HIV infection ( 33109212) Urinary metabolite levels in chronic kidney disease ( 31959995)	Age at first birth ( 34211149) Age at first sexual intercourse ( 34211149) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Attention deficit hyperactivity disorder ( 30478444) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Depression ( 33859377 29700475) Diabetic kidney disease ( 26305897) Diastolic blood pressure ( 30224653 33230300) Feeling miserable ( 29500382) Gastroesophageal reflux disease ( 34187846) General factor of neuroticism ( 30867560) General risk tolerance (MTAG) ( 30643258) Intelligence (MTAG) ( 29326435) Major depressive disorder ( 27479909) Medication use (calcium channel blockers) ( 31015401) Medication use (diuretics) ( 31015401) Metabolite levels ( 23823483) Mood instability ( 31168069) Multisite chronic pain ( 33830993 31194737) Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600) Pulse pressure ( 33230300) Rosacea symptom severity ( 29771307) Schizophrenia ( 33169155) Subclinical trait of interstitial lung disease (basilar percentage of high attenuation areas on CT scan) ( 28521775) Systolic blood pressure ( 33230300 30578418)
Interacting Genes		1 interacting genes: SORCS3	7 interacting genes: ACSM6 ATXN1 AZIN1 F8 IDE NGF RGS14
Entrez ID		142827	22986
HPRD ID		12565	12100
Ensembl ID		ENSG00000173124	ENSG00000156395
Uniprot IDs		Q6P461	Q86XB2 Q9UPU3
PDB IDs
Enriched GO Terms of Interacting Partners?
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