UBE2F and RC3H1

Number of citations of the paper that reports this interaction (PubMedID 26489670)
13

Data Source:
BioGRID (pull down)

		UBE2F	RC3H1
Description		ubiquitin conjugating enzyme E2 F (putative)	ring finger and CCCH-type domains 1
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GO Annotations	Cellular Component	Nucleus Cytosol	P-body Cytoplasmic Stress Granule
	Molecular Function	Protein Binding ATP Binding NEDD8 Transferase Activity NEDD8 Conjugating Enzyme Activity	RNA Binding Double-stranded RNA Binding MRNA Binding MRNA 3'-UTR Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding MiRNA Binding RNA Stem-loop Binding Ubiquitin Protein Ligase Activity CCR4-NOT Complex Binding
	Biological Process	Post-translational Protein Modification Protein Neddylation	Protein Polyubiquitination Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process B Cell Homeostasis Regulation Of Germinal Center Formation Negative Regulation Of Germinal Center Formation Ubiquitin-dependent Protein Catabolic Process Posttranscriptional Regulation Of Gene Expression Negative Regulation Of B Cell Proliferation P-body Assembly T Cell Proliferation T Cell Homeostasis Regulation Of MRNA Stability Negative Regulation Of T-helper Cell Differentiation Negative Regulation Of Activated T Cell Proliferation Lymph Node Development Spleen Development T Cell Receptor Signaling Pathway Regulation Of T Cell Receptor Signaling Pathway Positive Regulation Of MRNA Catabolic Process 3'-UTR-mediated MRNA Destabilization T Follicular Helper Cell Differentiation Cellular Response To Interleukin-1 Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of T-helper 17 Cell Differentiation Regulation Of MiRNA Metabolic Process
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Lean body mass ( 28552196)
Interacting Genes		11 interacting genes: CUL1 CUL5 DCUN1D1 DCUN1D2 DCUN1D5 LCN2 NAE1 PAX6 RC3H1 RNF34 UBA3	14 interacting genes: ICOS TNF TNFRSF4 UBE2A UBE2B UBE2D2 UBE2F UBE2G1 UBE2G2 UBE2L3 UBE2N UBE2V1 UBE2V2 UCP3
Entrez ID		140739	149041
HPRD ID		14812	13913
Ensembl ID		ENSG00000184182	ENSG00000135870
Uniprot IDs		Q969M7	B7ZMB3 B9EGU6 Q5TC82
PDB IDs		2EDI 3FN1 4GBA	3X1O 4QIK 4QIL 4ULW 4YWQ
Enriched GO Terms of Interacting Partners?
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