HDX and FHL5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HDX	FHL5
Description		highly divergent homeobox	four and a half LIM domains 5
Image
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Z Disc
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Dentures ( 31235808) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)	Cerebral blood flow ( 28627999) Coronary artery disease ( 29212778) Coronary heart disease ( 22319020) Headache ( 29397368) Metabolite levels ( 23823483) Migraine ( 22683712 27182965 23793025 27322543) Migraine - clinic-based ( 23793025) Migraine without aura ( 23793025 27322543) Myocardial infarction ( 33532862) Night sleep phenotypes ( 27126917) Pulse pressure ( 30578418) Spatial memory ( 31596458)
Interacting Genes		16 interacting genes: BOLA1 BOLA2 BOLA2B CCDC57 CTNNA3 FHL5 GCC1 LMO1 LNX1 MID2 POLR1C RTN4IP1 SUFU TSGA10 TTC5 ZBTB16	90 interacting genes: ABI2 ADAM12 ADAMTSL5 AGXT ANKRD55 ANKS1A BANP BBC3 BCL6B CATSPER1 CDC20B CFP CNNM3 COIL CREB1 CREM CRYBA2 CRYBA4 CTSZ DCDC2B DLGAP4 DMRT3 DNAL4 DTX2 FAM214B FAM71C FARS2 FEZF1 FHL2 GPS2 GSTP1 HAPLN2 HCK HDX HEY2 HOXA1 HOXB9 IL16 IP6K3 KIF17 KIR2DL4 LMO2 LRRC41 MAGOHB MISP MYOZ3 NEK6 NPDC1 NUFIP2 OTX1 PIN1 PLEKHA2 PLEKHN1 PPP1R18 PPP1R32 QRICH1 RAB26 RAB3IL1 RPS21 SAXO1 SCNM1 SDCBP SEC31A SHFL SLIT1 SMAD1 SPRY1 SRF TUSC2 TXN2 YPEL3 ZBTB16 ZNF124 ZNF131 ZNF23 ZNF250 ZNF251 ZNF408 ZNF417 ZNF440 ZNF446 ZNF564 ZNF581 ZNF587 ZNF613 ZNF688 ZNF764 ZNF766 ZNF792 ZNHIT1
Entrez ID		139324	9457
HPRD ID		06550	05497
Ensembl ID		ENSG00000165259	ENSG00000112214
Uniprot IDs		Q7Z353	Q5TD97
PDB IDs		2DA4	1X68
Enriched GO Terms of Interacting Partners?
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