ATF6B and LHX8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ATF6B	LHX8
Description		activating transcription factor 6 beta	LIM homeobox 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Endoplasmic Reticulum Membrane Protein-DNA Complex RNA Polymerase II Transcription Regulator Complex	Chromatin Female Germ Cell Nucleus Nucleus
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding CAMP Response Element Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Signal Transduction Endoplasmic Reticulum Unfolded Protein Response ATF6-mediated Unfolded Protein Response Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of ATF6-mediated Unfolded Protein Response Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress	Regulation Of Transcription By RNA Polymerase II Learning Or Memory Female Gonad Development Forebrain Neuron Development Neuron Differentiation Odontogenesis Of Dentin-containing Tooth
Pathways
Drugs
Diseases
GWAS		Age-related macular degeneration ( 23577725) Autism spectrum disorder or schizophrenia ( 28540026) Automobile speeding propensity ( 30643258) Blood protein levels ( 29875488 28240269) Blood protein levels in cardiovascular risk ( 28369058) Body shape index ( 34021172) Coronary artery disease ( 32469254) Inflammatory bowel disease ( 28067908) Intraocular pressure ( 29617998) Mean corpuscular volume ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Prostate cancer ( 23535732) Takayasu arteritis ( 25604533) Ulcerative colitis ( 28067908) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		10 interacting genes: ATF6 CDK6 CREBZF LHX8 MBTPS1 MBTPS2 NFYA NFYC PHOX2A XBP1	27 interacting genes: - ABI2 ATF2 ATF6B AXIN1 BANP CCHCR1 CRK CSNK2A1 EFS FIGLA FOSL2 FOXN1 GINS4 KLF3 KRT85 LDB1 LDB2 NEDD9 NUTM1 PLCG2 PRPF31 SCYL3 SUV39H1 TBC1D1 TBC1D22B ZBTB24
Entrez ID		1388	431707
HPRD ID		02992	17275
Ensembl ID		ENSG00000213676	ENSG00000162624
Uniprot IDs		A0A1U9X796 Q6AZW6 Q99941	Q68G74
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?