UBXN2B and PPP1R11

Number of citations of the paper that reports this interaction (PubMedID 33058883)
2

Data Source:
BioGRID (pull down)

		UBXN2B	PPP1R11
Description		UBX domain protein 2B	protein phosphatase 1 regulatory inhibitor subunit 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Golgi Apparatus Cytosol Spindle Pole Centrosome	Nucleus Cytoplasm
	Molecular Function	Protein Binding Ubiquitin Binding	Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 1 Binding Ubiquitin Protein Ligase Activity
	Biological Process	Autophagosome Assembly Establishment Of Mitotic Spindle Orientation Golgi Organization Nuclear Membrane Reassembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Mitotic Centrosome Separation Membrane Fusion Negative Regulation Of Protein Localization To Centrosome	Negative Regulation Of Cytokine Production Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Negative Regulation Of Phosphoprotein Phosphatase Activity Defense Response To Gram-positive Bacterium
Pathways
Drugs
Diseases
GWAS		Gallstone disease ( 27094239) LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Loneliness ( 27629369) Low density lipoprotein cholesterol levels ( 29403010 33339817) Medication use (HMG CoA reductase inhibitors) ( 31015401) Narcolepsy with cataplexy ( 23496005) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415) Total cholesterol levels ( 29403010 33339817) Triglyceride levels ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)	Anger ( 24489884) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Lipid metabolism phenotypes ( 22286219)
Interacting Genes		16 interacting genes: CRX FAM104A INCA1 MEOX1 MEOX2 NGLY1 PAX5 PAX6 PIN1 PPP1R11 PPP1R3A PPP1R7 UBXN6 VAT1L VCP XAF1	10 interacting genes: IFT20 LATS1 PPP1CA PPP1CB PPP1CC PPP1R3A TNF UBXN2B VCP YAF2
Entrez ID		137886	6992
HPRD ID		18973	09449
Ensembl ID		ENSG00000215114	ENSG00000204619
Uniprot IDs		E5RJ36 Q14CS0	A2BEK1 O60927
PDB IDs
Enriched GO Terms of Interacting Partners?
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