SSC4D and PTPMT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SSC4D	PTPMT1
Description		scavenger receptor cysteine rich family member with 4 domains	protein tyrosine phosphatase mitochondrial 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Membrane	Nucleus Mitochondrion Mitochondrial Inner Membrane
	Molecular Function	Scavenger Receptor Activity	Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatidylglycerophosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Endocytosis	Cardiolipin Biosynthetic Process Peptidyl-tyrosine Dephosphorylation Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways			Synthesis of PG
Drugs
Diseases
GWAS			Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Bipolar disorder ( 31043756) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Estimated glomerular filtration rate ( 30604766) Fruit consumption ( 32066663) Glomerular filtration rate ( 29403010) Hypertension ( 27618448) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Mean arterial pressure ( 27618448) Mood instability ( 31168069) Neuroticism ( 29255261) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271)
Interacting Genes		33 interacting genes: ATXN7L2 CATSPER1 CNNM3 COL8A1 CREB5 CYSRT1 ENKD1 GNE HAPLN2 HOXA1 HSD3B7 KRTAP10-8 KRTAP12-4 KRTAP13-2 KRTAP26-1 KRTAP3-3 MGAT5B NFKBID PCSK5 PLEKHN1 PLSCR4 PRKAB2 PTPMT1 RECK RHOU STK16 TEKT5 TFAP2D TLE5 TRIP13 TROAP TSC2 VASN	32 interacting genes: ADAMTSL4 CREB3L1 CYSRT1 GRN KRT31 KRT34 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-4 KRTAP3-1 KRTAP4-12 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 LCE2C MAPK6 MDFI MTUS2 NBPF19 NOTCH2NLA RGS20 SIAH1 SSC4D TAB1 TMEM14B TRIM27
Entrez ID		136853	114971
HPRD ID		06364	15151
Ensembl ID		ENSG00000146700	ENSG00000110536
Uniprot IDs		Q8WTU2	Q8WUK0
PDB IDs
Enriched GO Terms of Interacting Partners?
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