SLC9B2 and PGRMC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC9B2	PGRMC2
Description		solute carrier family 9 member B2	progesterone receptor membrane component 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Plasma Membrane Endosome Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Synaptic Vesicle Membrane Mitochondrial Membrane Sperm Principal Piece	Nuclear Envelope Endoplasmic Reticulum Endomembrane System Membrane Integral Component Of Membrane
	Molecular Function	Monovalent Cation:proton Antiporter Activity Protein Binding Lithium:proton Antiporter Activity Sodium:proton Antiporter Activity Identical Protein Binding	Steroid Hormone Receptor Activity Steroid Binding Protein Binding Heme Transmembrane Transporter Activity Heme Binding
	Biological Process	Sodium Ion Transport Metal Ion Transport Flagellated Sperm Motility Ion Transmembrane Transport Sodium Ion Transmembrane Transport Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Clathrin-dependent Endocytosis Proton Transmembrane Transport Positive Regulation Of Osteoclast Development	Heme Transport Steroid Hormone Mediated Signaling Pathway Adipose Tissue Development
Pathways		Stimuli-sensing channels	RHOA GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Type 2 diabetes ( 30054458)	Bone mineral density (total hip) ( 29883787)
Interacting Genes		1 interacting genes: PGRMC2	57 interacting genes: AQP10 ART5 BAG4 C5 COX20 CYB561D2 CYP4F2 DGAT2L6 DHRSX EI24 FA2H FAXDC2 FXYD6 FXYD6-FXYD2 GET3 GHITM GPR151 ITGAM ITPRIP LPAR3 MALL MFHAS1 MFSD5 ORMDL1 PEDS1-UBE2V1 PEX16 PGRMC1 PLLP PMP22 RNF8 RUSF1 SFXN1 SLC16A13 SLC30A8 SLC38A1 SLC39A13 SLC9B2 SMPD2 ST6GAL2 STX3 TAS2R19 TECR TF TMEM107 TMEM187 TMEM19 TMEM208 TMEM60 TMEM86A TMEM86B TSPAN2 UBXN8 VAPA VEZT YIPF2 ZDHHC21 ZFPL1
Entrez ID		133308	10424
HPRD ID		14051	09665
Ensembl ID		ENSG00000164038	ENSG00000164040
Uniprot IDs		A0A024RDJ7 B7Z488 B7Z676 E9PE63 Q86UD5	O15173
PDB IDs
Enriched GO Terms of Interacting Partners?
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