CPEB2 and ERI3

Number of citations of the paper that reports this interaction (PubMedID 22157746)
35

Data Source:
BioGRID (two hybrid)

		CPEB2	ERI3
Description		cytoplasmic polyadenylation element binding protein 2	ERI1 exoribonuclease family member 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Neuron Projection Synapse Messenger Ribonucleoprotein Complex
	Molecular Function	Translation Repressor Activity, MRNA Regulatory Element Binding RNA Binding MRNA 3'-UTR Binding GTPase Inhibitor Activity Translation Factor Activity, RNA Binding MRNA 3'-UTR AU-rich Region Binding Ribosome Binding Ribosomal Large Subunit Binding Ribosomal Small Subunit Binding	3'-5'-exoribonuclease Activity RNA Binding Metal Ion Binding
	Biological Process	Translation Cellular Response To Insulin Stimulus Negative Regulation Of GTPase Activity Cellular Response To Oxidative Stress Cellular Response To Arsenic-containing Substance Cellular Response To Hypoxia Negative Regulation Of Cytoplasmic Translational Elongation Negative Regulation Of Cytoplasmic Translation	Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
Pathways
Drugs
Diseases
GWAS		Cognitive flexibility ( 30134085) Triglyceride levels ( 32203549) Type 2 diabetes ( 33479058)	Anxiety ( 33859377) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
Interacting Genes		22 interacting genes: ATG2A ATP1B2 BSCL2 C2CD2L CAPN15 CC2D2A COPS7A ERI3 GAA GABBR1 GPX7 KEAP1 MT-ATP6 NECAB2 OTUB1 PIGS PSAP PUF60 SEMA4B SORBS3 SPARC TUBA1A	5 interacting genes: CENPO CPEB2 HOOK1 PRNP SHANK3
Entrez ID		132864	79033
HPRD ID		16744	15175
Ensembl ID		ENSG00000137449	ENSG00000117419
Uniprot IDs		A0A5K1VW61 A0A5K1VW71 A0A5K1VW79 A0A5K1VW93 Q7Z5Q1	B4DEX5 B4DN03 O43414
PDB IDs			2XRI
Enriched GO Terms of Interacting Partners?
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