GNPDA2 and MAGOHB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GNPDA2	MAGOHB
Description		glucosamine-6-phosphate deaminase 2	mago homolog B, exon junction complex subunit
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus Nucleoplasm Exon-exon Junction Complex Neuronal Cell Body U2-type Precatalytic Spliceosome U2-type Catalytic Step 1 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Glucosamine-6-phosphate Deaminase Activity Protein Binding Identical Protein Binding	RNA Binding Protein Binding
	Biological Process	Carbohydrate Metabolic Process Glucosamine Catabolic Process N-acetylglucosamine Catabolic Process UDP-N-acetylglucosamine Biosynthetic Process N-acetylneuraminate Catabolic Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Splicing, Via Spliceosome RNA Splicing MRNA Transport
Pathways		Glycolysis	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Adult body size ( 32376654) BMI (adjusted for smoking behaviour) ( 28443625) BMI at adiposity rebound ( 31840077) BMI in non-smokers ( 28443625) BMI in smokers ( 28443625) Body mass index ( 23563607 19079261 26961502 23669352 24861553 31453325 28892062 25673413 20935630 23583978 28448500) Body mass index (adult) ( 28430825) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Body mass index in physically inactive individuals ( 28448500) Body mass index variance ( 31453325) Body size at age 10 ( 32376654) Childhood body mass index ( 33045005 26604143) General risk tolerance (MTAG) ( 30643258) Hand grip strength ( 29691431) Hip circumference ( 25673412) Menarche (age at onset) ( 25231870) Metabolite levels ( 23823483) Obese vs. thin ( 30677029) Obesity ( 23563607) Obesity (extreme) ( 30677029) Refractive error ( 32231278) Systolic blood pressure ( 26969751) Type 2 diabetes ( 30297969 32499647 30718926) Waist circumference ( 31453325 25673412) Waist circumference variance ( 31453325)
Interacting Genes		7 interacting genes: AMDHD2 BEND4 DCAF4L1 ERRFI1 MAGOHB NTAQ1 TRIM27	73 interacting genes: ADAMTSL4 AMOTL2 BEND7 C18orf54 CALCOCO2 CARD10 CCDC102B CCDC106 CCDC33 DVL2 DVL3 EFHC2 FHL5 FXR1 GNPDA2 GOLGA2 GPANK1 HMG20A HSF2BP IHO1 IKZF1 IKZF3 INCA1 KRT40 KRT75 KRTAP1-1 KRTAP13-2 MID2 NDUFB7 PARD6B PAX7 PBX4 PKP2 PRPH PRPSAP1 PTPN21 RBAK RBM8A RBMX REL RUNDC3A SNW1 SPATA6 SPDYE4 STX11 TADA2A TCF4 TERF2 TERF2IP THAP7 TLE5 TRA2A TRA2B TRIM27 TRIM42 YWHAG ZBTB10 ZBTB42 ZFP14 ZFYVE1 ZNF19 ZNF250 ZNF398 ZNF426 ZNF438 ZNF446 ZNF449 ZNF547 ZNF566 ZNF57 ZNF620 ZNF774 ZNF835
Entrez ID		132789	55110
HPRD ID		13594	08544
Ensembl ID		ENSG00000163281	ENSG00000111196
Uniprot IDs		A0A024R9X5 Q8TDQ7	A0A023T6R1 F5H6P7 Q96A72
PDB IDs			5XJC 5YZG 6ICZ 6QDV
Enriched GO Terms of Interacting Partners?
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