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TMEM42 and LMNA
Number of citations of the paper that reports this interaction (PubMedID
24623722
)
32
Data Source:
BioGRID
(two hybrid)
TMEM42
LMNA
Description
transmembrane protein 42
lamin A/C
Image
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Membrane
Nucleus
Nuclear Envelope
Lamin Filament
Nucleoplasm
Cytosol
Nuclear Matrix
Nuclear Body
Nuclear Speck
Nuclear Membrane
Site Of Double-strand Break
Molecular Function
Protein Binding
Protein Binding
Biological Process
Protein Import Into Nucleus
Nuclear Envelope Organization
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Gene Expression
Regulation Of Cell Migration
Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity
Regulation Of Protein Stability
Protein Localization To Nucleus
Ventricular Cardiac Muscle Cell Development
Cellular Response To Hypoxia
Negative Regulation Of Mesenchymal Cell Proliferation
Negative Regulation Of Release Of Cytochrome C From Mitochondria
Positive Regulation Of Cell Aging
Positive Regulation Of Histone H3-K9 Trimethylation
Regulation Of Protein Localization To Nucleus
Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
DNA Double-strand Break Attachment To Nuclear Envelope
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
XBP1(S) activates chaperone genes
Signaling by BRAF and RAF1 fusions
Drugs
Diseases
GWAS
Acne (severe) (
24927181
)
Bipolar disorder (
31043756
)
Birth weight (
31043758
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (min-P) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Cortical thickness (min-P) (
32665545
)
Cortical thickness (MOSTest) (
32665545
)
Hip index (
34021172
)
Ischemic heart disease in rheumatoid arthritis (
30251476
)
Lung cancer in ever smokers (
28604730
)
Monocyte count (
32888494
)
Neutrophil count (
32888494
)
Ovarian cancer (
30557369
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Urate levels (
31578528
)
White blood cell count (
32888494
)
Interacting Genes
54 interacting genes:
AQP3
AQP6
BDKRB1
CD79A
DTX2
EBP
EDA
ELOVL4
ERGIC3
FAM174A
FAM209A
GET1
GJA8
GOLM2
GPR152
GPX8
HSD17B11
HSD17B13
LEPROTL1
LHFPL5
LMNA
MFF
MGAT5B
MMD
MMGT1
MRM1
MTIF3
NEMP1
PROP1
PSCA
RABAC1
RBPMS
REEP1
REEP2
RETREG3
RHBDD1
SAR1A
SCN3B
SEC11C
SERINC2
SHISAL1
SLC18A1
SLC34A2
SMIM14
SVOPL
TLX3
TM4SF19
TMEM147
TMEM14B
TMEM237
TMEM35A
TMEM74
VENTX
ZDHHC15
380 interacting genes:
ABCA9
ACOT7
ACTB
ADAM33
ADGRE2
ADGRG7
AGTRAP
AIG1
AKTIP
ALG3
ALG8
ALOX12
ALOX12B
ANKRD20A5P
ANXA6
AOC3
APOA2
APOD
APOL2
AQP1
AQP10
AQP3
ARHGEF16
ARL6IP1
ASGR1
ATP6V0C
BCL2L2
BNIP2
BNIP3
BNIP3L
BRICD5
BTN2A2
BYSL
C11orf24
C1QTNF1
C20orf141
C3orf52
C4orf3
C5
CACNG1
CASP1
CASP6
CCDC120
CCNG1
CD52
CD72
CD81
CDK1
CDS2
CENPP
CETN3
CFHR5
CHST1
CLCA4
CLDN10
CLDND2
CLEC1A
CLEC4A
CLK1
CLN6
CMTM3
CMTM5
CMTM7
CNIH3
COL8A2
COX14
CREB3
CRY2
CSGALNACT2
CTSA
CWF19L2
CXCL14
CXCL16
CYB561
CYB561D2
CYB5B
CYBC1
CYBRD1
DBNDD2
DDX24
DDX43
DEFB127
DERL1
DERL2
DNAJC30
DUS3L
DUSP13
EDDM3B
EGF
EIF3G
ELOA
EMD
ENTPD3
ERG28
F2RL1
FA2H
FAIM
FAM161A
FAM3C
FAM9B
FATE1
FAXDC2
FBXO7
FCER1A
FCER1G
FDFT1
FETUB
FLNA
FOS
FXYD3
FXYD6
GALNT2
GIN1
GJB2
GJB5
GOLGA2P10
GOLT1B
GOSR2
GPR108
GPR25
GRM2
GZMA
GZMB
HACD1
HCK
HMOX1
IFFO1
IFIT2
IGFBP5
INSIG2
ITGAM
ITM2B
IZUMO2
JAGN1
KASH5
KAT5
KCNK1
KCNK13
KIF12
KPNA6
KRT6A
KRTAP10-3
KRTAP10-7
LAMB1
LAT
LCP2
LEPROTL1
LHFPL5
LIMS2
LINC01587
LMBR1
LMNB1
LPAR3
LRP10
LVRN
MAL
MALL
MAPRE2
MARVELD1
MATR3
MCM5
MEOX1
MFAP1
MFSD5
MGLL
MGST3
MIP
MLIP
MMD2
MORF4L1
MRPS26
MS4A1
MTHFD2
MUTYH
MYADM
NAB2
NALCN
NARF
NAT8
NEU1
NINJ2
NIPAL3
NKG7
NOD2
NTAQ1
OGT
ORMDL1
ORMDL3
OSBPL8
OSTCP1
OSTF1
PAQR5
PARPBP
PCBP1
PCGF2
PCNA
PELI1
PERM1
PIAS2
PIK3R2
PKD2
PLLP
PLP1
PLP2
PLPP4
PMP22
PNKP
PNLIPRP1
PRELID3A
PRKCA
PRNP
PTPN9
PYGM
RABAC1
RANBP9
RB1
RBBP4
REEP6
RGS18
RHAG
RMDN2
RNF123
RPRM
RTN1
RTN3
RTN4
RUSF1
SACM1L
SBDS
SCARA3
SCARB2
SEC22A
SEC22B
SELENOK
SENP2
SERP1
SERP2
SERPINE1
SFT2D2
SFTPC
SGMS2
SH3RF2
SIAH1
SLC13A3
SLC1A1
SLC26A4-AS1
SLC2A5
SLC30A2
SLC30A3
SLC30A8
SLC35A1
SLC35A4
SLC35B2
SLC35B4
SLC38A7
SLC41A2
SLC7A1
SLN
SLU7
SMAD1
SMAD3
SMCO4
SMIM11
SMURF1
SMURF2
SNORC
SPANXC
SPANXD
SPG21
SPN
SREBF1
SRPK2
STAC
STAC2
STARD3
STX12
STX3
STX4
STX5
STX6
STX7
STX8
SUMO2
SUMO4
SVIL
SYCE1
SYNE1
SYNGR1
SYPL1
SYT6
TAP1
TCEA2
TCEANC
TDO2
TFRC
THBD
TM4SF20
TMEM107
TMEM109
TMEM11
TMEM120B
TMEM128
TMEM140
TMEM14A
TMEM14B
TMEM14C
TMEM199
TMEM201
TMEM203
TMEM208
TMEM218
TMEM222
TMEM230
TMEM234
TMEM243
TMEM267
TMEM41A
TMEM42
TMEM43
TMEM51
TMEM54
TMEM60
TMEM65
TMEM74
TMEM86A
TMPO
TMPRSS4
TNF
TNFRSF10C
TNFSF12
TNMD
TOR1A
TOR1AIP1
TRAM1L1
TRIM26
TRIM39
TSGA10
TSNARE1
TSPAN2
TSPAN33
TSPAN7
UBE2I
UBE2Q1
UBQLNL
UCHL5
UNC13D
UNC45A
UNC50
UPK1B
URB2
USE1
USP2
USP20
VAMP1
VAMP2
VAMP3
VAMP5
VKORC1
VMP1
VSTM1
VTI1B
WFDC2
YIPF1
YIPF6
YWHAQ
ZC2HC1C
ZDHHC15
ZDHHC24
ZMYM6
ZNF138
ZNF239
ZNF25
ZNF3
ZNF439
ZNF440
ZNF490
ZNF564
ZNF569
ZNF69
ZSCAN12
Entrez ID
131616
4000
HPRD ID
15540
01035
Ensembl ID
ENSG00000169964
ENSG00000160789
Uniprot IDs
Q69YG0
A0A384MQX1
P02545
Q5TCI8
PDB IDs
1IFR
1IVT
1X8Y
2XV5
2YPT
3GEF
3V4Q
3V4W
3V5B
6GHD
6JLB
6RPR
6SNZ
6YF5
6YJD
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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