COPB1 and TAPBP

Number of citations of the paper that reports this interaction (PubMedID 11884415)
16

Data Source:
HPRD (in vivo, in vitro)

		COPB1	TAPBP
Description		COPI coat complex subunit beta 1	TAP binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi-associated Vesicle Cytosol Plasma Membrane Membrane COPI Vesicle Coat Transport Vesicle Secretory Granule Membrane Intracellular Membrane-bounded Organelle Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane MHC Class I Peptide Loading Complex Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding ABC-type Peptide Antigen Transporter Activity MHC Class I Protein Binding Peptide Antigen Binding TAP1 Binding TAP2 Binding Unfolded Protein Binding TAP Complex Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport	MHC Class I Protein Complex Assembly MHC Class Ib Protein Complex Assembly Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Immune Response Regulation Of Gene Expression Peptide Transport Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Peptide Antigen Stabilization Regulation Of Protein Complex Stability Protein-containing Complex Assembly
Pathways		Neutrophil degranulation COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	ER-Phagosome pathway Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases
GWAS		HDL cholesterol ( 26780889) HDL cholesterol levels ( 32203549 28334899) Height ( 31562340) High chromosomal aberration frequency (total) ( 31586183) Hip circumference adjusted for BMI ( 34021172) Vitamin D levels ( 25208829)	Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576 29875488)
Interacting Genes		44 interacting genes: ADAM19 APP ARCN1 ARF1 BCAR1 COPE COPG1 COPG2 ERBIN FOXB1 GORAB GRB2 GTPBP4 HLA-DPB1 HLA-G ID1 IRAK3 KCNK3 KDELR1 KIAA1328 LINC00839 LZTS1 LZTS2 NUB1 PDGFRB PRKCE PTEN RGS2 RGS4 RHOQ SCYL1 SERTAD1 SNTA1 SPTBN1 TANK TAPBP TMED10 TRIM37 TTYH2 UBC UBQLN4 VPS18 WBP2 XRCC6	10 interacting genes: CALR COPB1 COPG1 COPG2 HLA-A HLA-C TAP1 TAP2 TNF UBC
Entrez ID		1315	6892
HPRD ID		02981	09061
Ensembl ID		ENSG00000129083	ENSG00000231925
Uniprot IDs		P53618	A0A024RCT1 A0A0A0MSV9 A0A0A0MT98 O15533
PDB IDs			3F8U 6ENY
Enriched GO Terms of Interacting Partners?
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