OTOL1 and IFT80

		OTOL1	IFT80
Description		otolin 1	intraflagellar transport 80
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Type IV Trimer Extracellular Space Extracellular Matrix	Cytoplasm Centrosome Cilium Intraciliary Transport Particle B Ciliary Basal Body Ciliary Tip 9+0 Non-motile Cilium
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding
	Biological Process	Extracellular Matrix Organization Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Otolith Mineralization Protein Homooligomerization	Osteoblast Differentiation Endochondral Ossification Growth Plate Cartilage Chondrocyte Differentiation Smoothened Signaling Pathway Osteoblast Proliferation Bone Mineralization Involved In Bone Maturation Negative Regulation Of Epithelial Cell Proliferation Limb Development Cilium Assembly Articular Cartilage Development Receptor Localization To Non-motile Cilium Non-motile Cilium Assembly Negative Regulation Of Non-canonical Wnt Signaling Pathway
Pathways			Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Aging (time to death) ( 21782286) Alcohol consumption (drinks per week) ( 30643258) Hepcidin/ferritin ratio ( 27846281) Schizophrenia ( 28991256 30285260) Schizophrenia x sex interaction ( 34099189) Type 2 diabetes ( 30130595)	Alanine aminotransferase levels ( 34315874) Aspartate aminotransferase levels ( 34315874) Bipolar disorder ( 31043756) LDL cholesterol ( 30275531) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Malaria ( 31844061)
Interacting Genes		2 interacting genes: IFT80 TRIM59	7 interacting genes: FGFR4 NMD3 OTOL1 PLXNA2 SLITRK3 UBXN10 ZBBX
Entrez ID		131149	57560
HPRD ID		19083	13853
Ensembl ID		ENSG00000182447	ENSG00000068885
Uniprot IDs		A6NHN0	Q9P2H3
PDB IDs
Enriched GO Terms of Interacting Partners?
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