TMEM182 and SYNE4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		TMEM182	SYNE4
Description		transmembrane protein 182	spectrin repeat containing nuclear envelope family member 4
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Integral Component Of Nuclear Outer Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Establishment Of Epithelial Cell Apical/basal Polarity
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first sexual intercourse ( 27089180) Blood pressure ( 24903457) Blood pressure (anthropometric measures interaction) ( 24903457) Chromium levels ( 26025379) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) General risk tolerance (MTAG) ( 30643258) Night sleep phenotypes ( 27126917) Number of sexual partners ( 30643258) Photic sneeze reflex ( 27182965) PR interval ( 30046033 32439900) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275 33082346) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (current vs never) ( 33082346) Smoking status (ever vs never smokers) ( 30643258) Sun-seeking behavior ( 32920024)
Interacting Genes		15 interacting genes: CLDN5 FNDC9 GJA8 GPR42 KLRC1 MALL MS4A3 PLP1 SMIM3 SUSD3 SYNE4 TMEM140 TMEM218 TMEM31 TSPAN12	57 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CLDN19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B IGFBP5 ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 PLPP6 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TCEA2 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B WDR62 ZNF250 ZNF648
Entrez ID		130827	163183
HPRD ID		08698	08776
Ensembl ID		ENSG00000170417	ENSG00000181392
Uniprot IDs		Q6ZP80	Q8N205
PDB IDs			6R16 6WMD
Enriched GO Terms of Interacting Partners?
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