COL17A1 and PLOD3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		COL17A1	PLOD3
Description		collagen type XVII alpha 1 chain	procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Basement Membrane Extracellular Space Endoplasmic Reticulum Lumen Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Hemidesmosome Extracellular Matrix Collagen-containing Extracellular Matrix	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength	Iron Ion Binding Protein Binding Procollagen-lysine 5-dioxygenase Activity L-ascorbic Acid Binding Procollagen Glucosyltransferase Activity Procollagen Galactosyltransferase Activity
	Biological Process	Cell-matrix Adhesion Epidermis Development Extracellular Matrix Organization Hemidesmosome Assembly	In Utero Embryonic Development Endothelial Cell Morphogenesis Protein O-linked Glycosylation Protein Localization Peptidyl-lysine Hydroxylation Neural Tube Development Collagen Fibril Organization Cellular Response To Hormone Stimulus Collagen Metabolic Process Vasodilation Hydroxylysine Biosynthetic Process Epidermis Morphogenesis Lung Morphogenesis Basement Membrane Assembly
Pathways		Collagen degradation Collagen biosynthesis and modifying enzymes Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Assembly of collagen fibrils and other multimeric structures Type I hemidesmosome assembly Collagen chain trimerization	Collagen biosynthesis and modifying enzymes
Drugs			Ascorbic acid
Diseases
GWAS		Cardiac hypertrophy ( 21348951)	Blood protein levels ( 30072576)
Interacting Genes		18 interacting genes: ACTN1 ACTN4 CLSTN1 CSTF2T CTNND1 DSP DST ITGA6 ITGB4 KRT18 LAD1 PLEC PLOD3 PNKP PPIL1 PPL UBQLN2 WHRN	20 interacting genes: CCDC85B COIL COL17A1 CRIP3 DPPA2 EFHC2 EHMT2 FAM153A IP6K2 KCTD9 KHNYN L3MBTL3 LINC00839 NAB2 RAB3IP RALY RHOU RHOXF2 SORBS3 ZNF620
Entrez ID		1308	8985
HPRD ID		00223	04347
Ensembl ID		ENSG00000065618	ENSG00000106397
Uniprot IDs		Q9UMD9	O60568 Q9UG85
PDB IDs			6FXK 6FXM 6FXR 6FXT 6FXX 6FXY
Enriched GO Terms of Interacting Partners?
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