C20orf85 and CACNB3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		C20orf85	CACNB3
Description		chromosome 20 open reading frame 85	calcium voltage-gated channel auxiliary subunit beta 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytosol Voltage-gated Calcium Channel Complex Membrane Apical Plasma Membrane Synapse L-type Voltage-gated Calcium Channel Complex
	Molecular Function	Protein Binding	Voltage-gated Calcium Channel Activity Calcium Channel Regulator Activity Protein Binding High Voltage-gated Calcium Channel Activity Protein Kinase Binding
	Biological Process		Calcium Ion Transport Chemical Synaptic Transmission Neuromuscular Junction Development T Cell Receptor Signaling Pathway Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Calcium Ion Transport Into Cytosol Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Protein Localization To Plasma Membrane Positive Regulation Of Protein Targeting To Membrane Cellular Response To Oxygen-glucose Deprivation Regulation Of Membrane Repolarization During Action Potential Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Membrane Hyperpolarization Negative Regulation Of Detection Of Mechanical Stimulus Involved In Sensory Perception Of Touch Positive Regulation Of Excitatory Postsynaptic Potential
Pathways			Presynaptic depolarization and calcium channel opening Adrenaline,noradrenaline inhibits insulin secretion NCAM1 interactions Regulation of insulin secretion Regulation of insulin secretion
Drugs			Ergocalciferol Enflurane Ranolazine Phenytoin Topiramate Nimodipine Spironolactone Magnesium sulfate Levomenthol Miconazole Amiodarone Mibefradil Dronedarone Trimebutine Benidipine Cilnidipine Lacidipine Manidipine Butamben Bioallethrin Bioallethrin Fish oil
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Obesity-related traits ( 23251661) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		23 interacting genes: ACTN3 ALKBH7 ASPG CABP2 CACNB3 CASK CNOT2 DTX2 EFHC1 FHL2 KLHL2 KLHL20 KRTAP19-6 KRTAP3-1 KRTAP6-2 KRTAP8-1 LCN2 MAD2L2 OIP5 PFDN5 RBPMS TTC19 TUBB1	13 interacting genes: C20orf85 CACNA1B CACNA1C CDK2 CEP76 CIAPIN1 CTBP2 FASLG GEM MEOX1 MTUS2 SKIV2L SYT1
Entrez ID		128602	784
HPRD ID		12787	11879
Ensembl ID		ENSG00000124237	ENSG00000167535
Uniprot IDs		Q9H1P6	P54284
PDB IDs
Enriched GO Terms of Interacting Partners?
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