CNTF and TIMM10

		CNTF	TIMM10
Description		ciliary neurotrophic factor	translocase of inner mitochondrial membrane 10
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Axon	Mitochondrion Mitochondrial Inner Membrane TIM23 Mitochondrial Import Inner Membrane Translocase Complex Mitochondrial Intermembrane Space Mitochondrial Intermembrane Space Protein Transporter Complex
	Molecular Function	Cytokine Activity Ciliary Neurotrophic Factor Receptor Binding Interleukin-6 Receptor Binding Protein Binding Growth Factor Activity Protein-containing Complex Binding	Protein Binding Zinc Ion Binding Membrane Insertase Activity Protein Homodimerization Activity Chaperone Binding
	Biological Process	Signal Transduction Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Photoreceptor Cell Differentiation Regulation Of Retinal Cell Programmed Cell Death Astrocyte Activation Muscle Organ Morphogenesis Neuron Development Positive Regulation Of Axon Regeneration Ciliary Neurotrophic Factor-mediated Signaling Pathway	Protein Targeting To Mitochondrion Sensory Perception Of Sound Protein Insertion Into Mitochondrial Inner Membrane
Pathways		IL-6-type cytokine receptor ligand interactions	Mitochondrial protein import Mitochondrial protein import
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Inflammatory bowel disease ( 23128233) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) Ulcerative colitis ( 28067908)	Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		14 interacting genes: AK8 APOE CNTFR CYSRT1 IL6R IL6ST KRT31 KRT40 LIFR NDUFAB1 RDM1 TEPSIN TIMM10 TRIP6	8 interacting genes: - CNTF CREB3 DAGLA HAGH TBC1D21 TKFC ZNF655
Entrez ID		1270	26519
HPRD ID		00347	03768
Ensembl ID		ENSG00000242689	ENSG00000134809
Uniprot IDs		P26441	P62072
PDB IDs		1CNT	2BSK 7CGP
Enriched GO Terms of Interacting Partners?
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