CCDC43 and KLHL2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

		CCDC43	KLHL2
Description		coiled-coil domain containing 43	kelch like family member 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Ruffle Cytoplasm Cytosol Actin Cytoskeleton Lamellipodium Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding	Actin Binding Protein Binding Identical Protein Binding
	Biological Process		Protein Ubiquitination
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Cognitive function ( 24684796) General cognitive ability ( 29844566) Neuroticism ( 27067015)
Interacting Genes		5 interacting genes: KLHL2 LRRK2 MFHAS1 PNKP TINF2	32 interacting genes: ACTC1 BCAM BYSL C20orf85 CCDC43 CDC37 CLK2 CUL3 CWC22 ELOA FRAS1 KEAP1 KLHL12 KLHL3 MFAP1 NAP1L2 NTAQ1 PADI6 PIBF1 POLR3C SDCBP TMA16 TNPO2 TRIM50 TXNDC12 UBE2C UBE2D1 UBE2I UCK1 WNK1 WNK4 ZNF114
Entrez ID		124808	11275
HPRD ID		08107	09311
Ensembl ID		ENSG00000180329	ENSG00000109466
Uniprot IDs		Q96MW1	B4DFZ5 E9PEX9 O95198
PDB IDs			2XN4 4CHB
Enriched GO Terms of Interacting Partners?
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