LRR1 and PFKFB4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LRR1	PFKFB4
Description		leucine rich repeat protein 1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Cytosol
	Molecular Function	Protein Binding	6-phosphofructo-2-kinase Activity Fructose-2,6-bisphosphate 2-phosphatase Activity Protein Binding ATP Binding
	Biological Process	Protein Ubiquitination	Fructose Metabolic Process Fructose 2,6-bisphosphate Metabolic Process Dephosphorylation Carbohydrate Phosphorylation
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Regulation of glycolysis by fructose 2,6-bisphosphate metabolism
Drugs			Phosphoaminophosphonic Acid-Adenylate Ester Fructose-6-phosphate
Diseases
GWAS			Bitter beverage consumption ( 31046077) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Mental health study participation (completed survey) ( 31263887) Morning person ( 30696823) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908 25082827) Waist-hip index ( 34021172)
Interacting Genes		7 interacting genes: CDKN1A MTUS2 PFKFB4 PNMA2 TNFRSF9 TRIP13 UBE2D1	8 interacting genes: CCDC102B CDC23 CSNK2B GADD45A GSK3B LRR1 PFKFB1 PJA1
Entrez ID		122769	5210
HPRD ID		15164	05613
Ensembl ID		ENSG00000165501	ENSG00000114268
Uniprot IDs		A0A384MTQ0 Q6AWA7 Q96L50	B7Z5C3 Q16877 Q5XLC3 Q66S35
PDB IDs
Enriched GO Terms of Interacting Partners?
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