TRAPPC6B and TRAPPC12

Number of citations of the paper that reports this interaction (PubMedID 26186194)
524

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)

		TRAPPC6B	TRAPPC12
Description		trafficking protein particle complex subunit 6B	trafficking protein particle complex subunit 12
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex	Kinetochore Nucleus Nucleoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol TRAPP Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Nervous System Development Regulation Of GTPase Activity	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Metaphase Plate Congression Regulation Of Kinetochore Assembly Positive Regulation Of Protein Localization To Kinetochore
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	RAB GEFs exchange GTP for GDP on RABs
Drugs		S-palmitoyl-L-cysteine
Diseases
GWAS			Neuritic plaques or neurofibrillary tangles or cerebral amyloid angiopathy (pleiotropy) ( 29458411) Serum immune biomarker levels ( 32066700)
Interacting Genes		7 interacting genes: TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3L TRAPPC6A TRAPPC8	13 interacting genes: ARNTL FBXO7 HNRNPA2B1 LIN7B MTDH RSKR TFCP2 TRAPPC10 TRAPPC3L TRAPPC4 TRAPPC6A TRAPPC6B TRAPPC9
Entrez ID		122553	51112
HPRD ID		18221	15580
Ensembl ID		ENSG00000182400	ENSG00000171853
Uniprot IDs		Q86SZ2	A0A0J9YXQ9 Q8WVT3
PDB IDs		2BJN 2CFH 3KXC
Enriched GO Terms of Interacting Partners?
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