ERP27 and PDIA3

Number of citations of the paper that reports this interaction (PubMedID 16940051)
17

Data Source:
HPRD (in vitro, in vivo)

		ERP27	PDIA3
Description		endoplasmic reticulum protein 27	protein disulfide isomerase family A member 3
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen	Extracellular Space Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Lumen Focal Adhesion Cell Surface Melanosome MHC Class I Peptide Loading Complex Phagocytic Vesicle Recycling Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding	RNA Binding Protein Disulfide Isomerase Activity Cysteine-type Endopeptidase Activity Phospholipase C Activity Protein Binding Protein-disulfide Reductase Activity Disulfide Oxidoreductase Activity Identical Protein Binding
	Biological Process	Protein Folding Response To Unfolded Protein Response To Endoplasmic Reticulum Stress	Protein Folding Proteolysis Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Cellular Response To Interleukin-7 Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways			ER-Phagosome pathway ER-Phagosome pathway Calnexin/calreticulin cycle Antigen Presentation: Folding, assembly and peptide loading of class I MHC Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs			Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Finger osteoarthritis severity (hand Klsum) ( 33055079) Hand grip strength ( 29313844) Hand osteoarthritis severity (hand Klsum) ( 33055079) Low hand grip strength (60 years and older) (EWGSOP) ( 33510174) Osteoarthritis of the hand ( 28855172)	Blood protein levels ( 30072576) Lead levels ( 26025379) Liver volume ( 34128465) Triglyceride levels ( 32203549)
Interacting Genes		11 interacting genes: BLOC1S2 C12orf60 EEF1D GOLGA8F MED20 PDIA3 SGTA UBL4A UBQLN1 UBQLN2 UBQLN4	25 interacting genes: APP BACE1 CACNB2 CALR CANX ERO1A ERP27 ESR1 FBLN5 GYPC HLA-A IFNG LINC01554 MDM2 MTNR1B OGT PCAT1 PLCB2 SEC11A SLC12A3 SLC2A1 STAT3 SUMO4 TAP1 UBE3A
Entrez ID		121506	2923
HPRD ID		08723	03625
Ensembl ID		ENSG00000139055	ENSG00000167004
Uniprot IDs		F5GYS6 Q96DN0	P30101 V9HVY3
PDB IDs		2L4C 4F9Z	2ALB 2DMM 2H8L 3F8U 6ENY
Enriched GO Terms of Interacting Partners?
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