TPP1 and NMB

Number of citations of the paper that reports this interaction (PubMedID 15158442)
3

Data Source:
HPRD (in vitro)

		TPP1	NMB
Description		tripeptidyl peptidase 1	neuromedin B
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GO Annotations	Cellular Component	Lysosome Golgi Apparatus Melanosome Lysosomal Lumen Membrane Raft Recycling Endosome Extracellular Exosome	Extracellular Region Neuron Projection
	Molecular Function	Endopeptidase Activity Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Tripeptidyl-peptidase Activity Lysophosphatidic Acid Binding Peptide Binding Metal Ion Binding Sulfatide Binding	Hormone Activity Neuropeptide Hormone Activity Protein Binding Neuromedin B Receptor Binding
	Biological Process	Proteolysis Lipid Metabolic Process Lysosome Organization Nervous System Development Central Nervous System Development Protein Catabolic Process Epithelial Cell Differentiation Peptide Catabolic Process Bone Resorption Neuromuscular Process Controlling Balance Protein Localization To Chromosome, Telomeric Region Lysosomal Protein Catabolic Process	Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Glucose Homeostasis Positive Regulation Of Hormone Secretion Negative Regulation Of Hormone Secretion Arachidonic Acid Secretion
Pathways		XBP1(S) activates chaperone genes	Peptide ligand-binding receptors G alpha (q) signalling events
Drugs
Diseases
GWAS		Malaria ( 31844061)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Blood protein levels ( 30072576) Creatine kinase levels ( 29403010) Dilated cardiomyopathy ( 33495596) Dilated cardiomyopathy (MTAG) ( 33495596) P wave terminal force ( 28794112) Schizophrenia ( 29483656)
Interacting Genes		7 interacting genes: CTC1 NMB OGT POT1 STN1 TERT TINF2	12 interacting genes: BIRC2 CCNO CORO2B FBXL22 GADD45G GLCE KIF23 MAP2K5 MRPS5 NMBR PTPRZ1 TPP1
Entrez ID		1200	4828
HPRD ID		06415	01210
Ensembl ID		ENSG00000166340	ENSG00000197696
Uniprot IDs		O14773	P08949
PDB IDs		1R60 3EDY 3EE6	1C98 1C9A
Enriched GO Terms of Interacting Partners?
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