ZFYVE27 and SACM1L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZFYVE27	SACM1L
Description		zinc finger FYVE-type containing 27	SAC1 like phosphatidylinositide phosphatase
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Cytosol Integral Component Of Endoplasmic Reticulum Membrane Axon Dendrite Growth Cone Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Membrane Endoplasmic Reticulum Tubular Network	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Endoplasmic Reticulum Membrane Endoplasmic Reticulum-plasma Membrane Contact Site
	Molecular Function	Protein Binding Identical Protein Binding Protein Self-association Metal Ion Binding	Phosphatidylinositol-3-phosphatase Activity Protein Binding Phosphatase Activity Phosphatidylinositol Bisphosphate Phosphatase Activity Phosphatidylinositol Phosphate 4-phosphatase Activity Phosphatidylinositol-4-phosphate Phosphatase Activity
	Biological Process	Vesicle-mediated Transport Neuron Projection Development Positive Regulation Of Axon Extension Neurotrophin TRK Receptor Signaling Pathway Endoplasmic Reticulum Tubular Network Formation Protein Localization To Plasma Membrane	Phosphatidylinositol Biosynthetic Process Phosphatidylinositol Dephosphorylation
Pathways			Synthesis of PIPs at the ER membrane Synthesis of PIPs at the Golgi membrane
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Macular telangiectasia type 2 ( 33654266) Response to anti-depressant treatment in major depressive disorder ( 22041458) Serum metabolite levels ( 33031748) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		18 interacting genes: APP GIMAP1 GIMAP5 IER3IP1 ORMDL1 OTOP3 PIP4P2 SACM1L SEC22A SLC30A8 SLC66A2 STX7 TMEM128 TMEM14C TMEM243 TMEM65 TSPAN2 YIF1A	35 interacting genes: ACKR2 AQP6 ARL13B CD79A COPA COPB2 COPG1 CREB3 CREB3L1 DHRS7 EBP FFAR2 FMO3 GPR151 GPR152 HSD17B13 JAGN1 LMNA MFF MFSD14B MTERF2 ODF4 PRKCA RNF19B RTN3 SCN3B SLC10A1 SLC10A6 SLC35A5 SLC35C2 SLC7A1 TMEM167B TMX2 VEZT ZFYVE27
Entrez ID		118813	22908
HPRD ID		15735	07587
Ensembl ID		ENSG00000155256	ENSG00000211456
Uniprot IDs		A0A0S2Z627 B7Z6J9 Q5T4F4	B4DVV3 E9PGZ4 Q9NTJ5
PDB IDs		1X4U
Enriched GO Terms of Interacting Partners?
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