UBE2J2 and ELOVL7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		UBE2J2	ELOVL7
Description		ubiquitin conjugating enzyme E2 J2	ELOVL fatty acid elongase 7
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GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity	Protein Binding Fatty Acid Elongase Activity 3-oxo-arachidoyl-CoA Synthase Activity 3-oxo-cerotoyl-CoA Synthase Activity 3-oxo-lignoceronyl-CoA Synthase Activity Very-long-chain 3-ketoacyl-CoA Synthase Activity
	Biological Process	Protein Polyubiquitination Response To Unfolded Protein Ubiquitin-dependent ERAD Pathway Positive Regulation Of Protein Targeting To Mitochondrion	Unsaturated Fatty Acid Biosynthetic Process Fatty Acid Elongation, Saturated Fatty Acid Sphingolipid Biosynthetic Process Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongation, Polyunsaturated Fatty Acid Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process
Pathways		E3 ubiquitin ligases ubiquitinate target proteins Antigen processing: Ubiquitination & Proteasome degradation	Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 28067908) Systemic lupus erythematosus ( 28714469) Ulcerative colitis ( 28067908)	Age at first sexual intercourse ( 34211149) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cortical surface area ( 32963231) Cortical surface area (MOSTest) ( 32665545) Household income ( 31844048) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mean platelet volume ( 32888494 27863252) Multiple system atrophy ( 27629089) Parkinson's disease ( 32201043 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Smoking initiation (ever regular vs never regular) ( 30679032) Subcortical volume (MOSTest) ( 32665545) Working memory ( 31598132)
Interacting Genes		22 interacting genes: AQP6 ATP13A2 ELOVL7 FBXO7 HECW1 HERC4 ITCH MDM2 MGRN1 NEDD4L PRKN PUSL1 RBP1 RNF10 TMEM14B TRIM25 TRIM59 UBA1 UBC UBE2G2 WWP2 XIAP	12 interacting genes: ADGRE2 DTNBP1 EMP3 LRCH4 RTP2 SERF1A SERF1B SLC41A1 SYNJ2BP TMEM14C UBE2J2 VAMP1
Entrez ID		118424	79993
HPRD ID		15600	18700
Ensembl ID		ENSG00000160087	ENSG00000164181
Uniprot IDs		A0A024R075 A6NGS0 Q8N2K1	A1L3X0 D6RHD0
PDB IDs		2F4W	6Y7F
Enriched GO Terms of Interacting Partners?
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