SLC26A8 and PRIM1

		SLC26A8	PRIM1
Description		solute carrier family 26 member 8	DNA primase subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Nucleoplasm Alpha DNA Polymerase:primase Complex Membrane
	Molecular Function	Chloride Channel Activity Protein Binding Secondary Active Sulfate Transmembrane Transporter Activity Bicarbonate Transmembrane Transporter Activity Chloride Transmembrane Transporter Activity Sulfate Transmembrane Transporter Activity Anion:anion Antiporter Activity Oxalate Transmembrane Transporter Activity	Magnesium Ion Binding DNA Primase Activity Protein Binding Zinc Ion Binding Ribonucleotide Binding
	Biological Process	Anion Transport Chloride Transport Sulfate Transport Bicarbonate Transport Oxalate Transport Flagellated Sperm Motility Sperm Capacitation Meiotic Cell Cycle Sulfate Transmembrane Transport Chloride Transmembrane Transport	DNA Replication, Synthesis Of RNA Primer
Pathways			Inhibition of replication initiation of damaged DNA by RB1/E2F1 Polymerase switching on the C-strand of the telomere Telomere C-strand synthesis initiation DNA replication initiation Activation of the pre-replicative complex Polymerase switching Removal of the Flap Intermediate Processive synthesis on the lagging strand Defective pyroptosis
Drugs
Diseases
GWAS		Antidepressant treatment resistance (> 2 drugs prescribed) ( 30700811)	Appendicular lean mass ( 33097823) Asthma ( 31619474) Height ( 31562340) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Menopause (age at onset) ( 22267201 26414677) Monocyte count ( 32888494) Plateletcrit ( 32888494 27863252) Red blood cell count ( 29403010)
Interacting Genes		2 interacting genes: PRIM1 RACGAP1	15 interacting genes: MDC1 MRPL38 NFE2 OGT PDE1B PRIM2 RAB5B RARG RPS26 SENP1 SLC11A2 SLC26A8 STAT6 TP53 YIF1A
Entrez ID		116369	5557
HPRD ID		12241	08899
Ensembl ID		ENSG00000112053	ENSG00000198056
Uniprot IDs		A0A024RCV0 Q96RN1	P49642
PDB IDs			4BPU 4BPW 4BPX 4LIK 4LIL 4MHQ 4RR2 5EXR 6R4S 6R4T 6R4U 6R5D 6R5E 6RB4
Enriched GO Terms of Interacting Partners?
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