CYGB and ARHGAP8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CYGB	ARHGAP8
Description		cytoglobin	Rho GTPase activating protein 8
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Neuron Projection Neuronal Cell Body	Cytosol
	Molecular Function	Catalase Activity Peroxidase Activity Oxygen Carrier Activity Iron Ion Binding Protein Binding Oxygen Binding Heme Binding Fatty Acid Peroxidase Activity	GTPase Activator Activity Protein Binding
	Biological Process	Response To Hypoxia Response To Oxidative Stress Negative Regulation Of Fibroblast Migration Oxygen Transport Fatty Acid Oxidation Negative Regulation Of Collagen Biosynthetic Process Cellular Oxidant Detoxification Negative Regulation Of Hepatic Stellate Cell Activation	Signal Transduction Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of ERK1 And ERK2 Cascade
Pathways		eNOS activation Intracellular oxygen transport	RHOA GTPase cycle
Drugs
Diseases
GWAS			Binge eating behaviour in bipolar disorder ( 29391396) Body mass index ( 28552196) Electroencephalographic traits in alcoholism ( 22554406) Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600) Weight ( 28552196)
Interacting Genes		11 interacting genes: ARHGAP8 ATP13A2 CD300C DDI1 FAAP100 LRATD1 MZT1 PRR5-ARHGAP8 PRRG4 TBC1D16 WBP11	6 interacting genes: BNIP2 CTTN CYGB RHOA SH3GL1 ZMYND12
Entrez ID		114757	23779
HPRD ID		06479	06448
Ensembl ID		ENSG00000161544	ENSG00000241484
Uniprot IDs		A0A1K0FUB6 Q8WWM9	P85298 Q6PJW1
PDB IDs		1UMO 1URV 1URY 1UT0 1UX9 1V5H 2DC3 3AG0 4B3W
Enriched GO Terms of Interacting Partners?
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