| Description |
cholinergic receptor nicotinic beta 4 subunit |
cholinergic receptor nicotinic alpha 2 subunit |
| Image |
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| GO Annotations |
Cellular Component |
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| Molecular Function |
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| Biological Process |
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| Pathways |
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| Drugs |
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| Diseases |
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| GWAS |
- Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
- Attention function in attention deficit hyperactive disorder ( 26174813)
- Autism spectrum disorder or schizophrenia ( 28540026)
- Benign childhood epilepsy with centro-temporal spikes ( 32580138)
- BMI (smoking interaction) ( 28443625)
- BMI in smokers ( 28443625)
- Body mass index (joint analysis main effects and smoking interaction) ( 28443625)
- Chronic obstructive pulmonary disease ( 30804561)
- Chronic obstructive pulmonary disease x ever smoker interaction (1df) ( 33106845)
- Coronary artery disease ( 32469254 33020668)
- Diffusing capacity of carbon monoxide ( 30694715)
- Exhaled carbon monoxide levels ( 25072098)
- Gut microbiota relative abundance (Parabacteroides) ( 33208821)
- Lung adenocarcinoma ( 28604730)
- Lung cancer ( 31577861 28604730 18385738 18780872)
- Lung cancer in ever smokers ( 28604730)
- Nicotine dependence ( 18385739 26440539)
- Post bronchodilator FEV1 ( 26634245)
- Post bronchodilator FEV1/FVC ratio ( 26634245)
- Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
- Refractive error ( 32231278)
- Schizophrenia ( 25056061 29483656)
- Small cell lung carcinoma ( 28604730)
- Smoking status (heavy vs light) ( 28520984)
- Squamous cell lung carcinoma ( 28604730)
- Sudden cardiac arrest ( 21658281)
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- Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
- Autism spectrum disorder or schizophrenia ( 28540026)
- Cannabis use disorder ( 33096046 31209380)
- Lung cancer ( 28604730)
- Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901)
- Schizophrenia ( 29483656)
- Smoking status (current vs mixed) ( 33082346)
- Smoking status (current vs never) ( 33082346)
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| Interacting Genes |
8 interacting genes:
CHRNA2
CHRNA3
CHRNA4
CHRNA5
LARP7
MEOX2
SLC2A1
UBQLN1
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2 interacting genes:
CHRNB2
CHRNB4
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| Entrez ID |
1143 |
1135 |
| HPRD ID |
00337 |
00332 |
| Ensembl ID |
ENSG00000117971
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ENSG00000120903
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| Uniprot IDs |
P30926
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Q15822
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| PDB IDs |
2ASG
6PV7
6PV8
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5FJV
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| Enriched GO Terms of Interacting Partners? |
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| Tagcloud ? |
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| Tagcloud (Difference) ? |
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| Tagcloud (Intersection) ? |
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