BUD23 and OAS1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		BUD23	OAS1
Description		BUD23 rRNA methyltransferase and ribosome maturation factor	2'-5'-oligoadenylate synthetase 1
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Perinuclear Region Of Cytoplasm	Extracellular Region Nucleus Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol Membrane
	Molecular Function	RNA Binding Protein Binding Methyltransferase Activity RRNA (guanine) Methyltransferase Activity Protein Heterodimerization Activity	2'-5'-oligoadenylate Synthetase Activity Double-stranded RNA Binding Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Chromatin Organization RRNA (guanine-N7)-methylation Positive Regulation Of RRNA Processing	Glucose Metabolic Process Response To Virus Positive Regulation Of Interferon-beta Production Positive Regulation Of Tumor Necrosis Factor Production Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Cellular Response To Interferon-beta Glucose Homeostasis Defense Response To Bacterium Surfactant Homeostasis Negative Regulation Of Viral Genome Replication Defense Response To Virus Negative Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Ribonuclease Activity Interleukin-27-mediated Signaling Pathway Positive Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of IP-10 Production Cellular Response To Virus Antiviral Innate Immune Response Negative Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol	Interferon gamma signaling OAS antiviral response Interferon alpha/beta signaling
Drugs			Cysteine-S-acetamide
Diseases
GWAS			Blood protein levels ( 30072576 29875488) Body mass index ( 26426971) Glycemic traits ( 23575436) Low HDL-cholesterol levels ( 31006500) Response to fenofibrate (adiponectin levels) ( 23149075) Right-sided colonic diverticulosis ( 31089239) Urate levels ( 31578528)
Interacting Genes		5 interacting genes: DNAAF5 OAS1 PKN1 TRMT112 VCP	11 interacting genes: ACTN1 BBS4 BUD23 COG6 EXOC5 GOLGA2 HOOK2 PRMT6 RPL30 RUFY1 TRIM27
Entrez ID		114049	4938
HPRD ID		15659	08879
Ensembl ID		ENSG00000071462	ENSG00000089127
Uniprot IDs		O43709	P00973
PDB IDs		6G4W	4IG8
Enriched GO Terms of Interacting Partners?
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