OIP5 and AGXT

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		OIP5	AGXT
Description		Opa interacting protein 5	alanine--glyoxylate and serine--pyruvate aminotransferase
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromocenter Cajal Body Nuclear Speck Intracellular Membrane-bounded Organelle	Mitochondrial Matrix Peroxisome Peroxisomal Matrix Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Identical Protein Binding Metal Ion Binding	Serine-pyruvate Transaminase Activity Protein Binding Alanine-glyoxylate Transaminase Activity Transaminase Activity Amino Acid Binding Pyridoxal Phosphate Binding Identical Protein Binding Protein Homodimerization Activity Protein Self-association
	Biological Process	Cell Cycle Chromosome Segregation Cell Communication CENP-A Containing Nucleosome Assembly Cell Division	Glyoxylate Catabolic Process Glycine Biosynthetic Process, By Transamination Of Glyoxylate L-cysteine Catabolic Process L-alanine Catabolic Process Pyruvate Biosynthetic Process Glyoxylate Metabolic Process Response To Glucocorticoid Response To CAMP
Pathways		Deposition of new CENPA-containing nucleosomes at the centromere	Glyoxylate metabolism and glycine degradation Peroxisomal protein import Peroxisomal protein import
Drugs			Pyridoxal phosphate Serine Glycine Alanine Aminooxyacetic acid N(6)-(pyridoxal phosphate)-L-lysine 4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Ulcerative colitis ( 28067908)	Blood metabolite levels ( 24816252) Height ( 25282103 31562340) Urinary metabolites ( 26352407)
Interacting Genes		142 interacting genes: A1CF ABI2 ABI3 ABL2 AGXT BCAS2 BEX2 BFSP2 BLOC1S5 BRAF C1orf94 C20orf85 C21orf91 C7orf31 C7orf57 CASP10 CBY2 CCDC22 CCDC24 CCHCR1 CDR2L CEP170P1 CEP57 CERK CHCHD2 COX5B CRACR2A CTNNA3 DMRT3 DTNBP1 DTX2 DUSP21 EFHC1 EIF4ENIF1 ESS2 FAM161B FAM222B FOXJ1 FSD2 GADD45GIP1 GCC1 GEM GLIS2 GPANK1 GPS2 HAPLN2 HGS HJURP HOXB5 HOXB9 HOXC8 HSF4 IL16 KANK2 KDM1A KIF9 KLHL38 KLHL42 KNSTRN KRT14 KRT15 KRT27 KRT3 KRT35 KRT37 KRT40 KRT6B KRT75 KRT81 KRT83 KRT86 KRTAP13-2 KRTAP19-5 KRTAP19-6 LENG1 MED4 MEIS2 MGAT5B MIIP MIS18A MISP MORN3 MYEF2 MYRIP NDUFAB1 NECAB2 NUP54 NUP62 P4HA3 PATZ1 PEX19 PHETA1 PITX2 PLAGL2 POLR2J POU6F2 PPP1R32 PRR35 PSMB1 RAB26 RABGEF1 RAF1 RARG RIBC1 RUNX1T1 RUSC1 S100Z SAMD7 SAXO1 SHISA6 SKIL SMARCE1 SNRNP25 SNRPB SOHLH1 SORBS3 SPATA24 SYCE1L TEKT3 TEX12 TFAP2D TFIP11 TIMM8A TLX3 TMPO TPM3 TPRX1 TRIB3 TRIM73 TRIP6 TROAP TSSK3 USHBP1 USP2 USP54 VPS39 WASHC1 YTHDF1 ZIC1 ZMAT1 ZNF417 ZNF655	40 interacting genes: ACAT1 ATXN1L BATF3 C11orf1 C19orf54 CHIC2 CYSRT1 EFS FAM168B FHL5 FNTB FOSB GLP1R HOXA1 KRT31 KRT34 KRT37 KRT40 KRTAP1-1 KRTAP12-3 KRTAP3-1 KRTAP6-3 KRTAP8-1 KRTAP9-2 LPXN LYN MDFI MORN5 NBPF19 NOTCH2NLA OIP5 PEX5 PLA2G10 PRDM6 PRICKLE4 RFX6 SNCAIP SPRYD7 TRAPPC14 TTC19
Entrez ID		11339	189
HPRD ID		09352	05048
Ensembl ID		ENSG00000104147	ENSG00000172482
Uniprot IDs		A0A024R9N0 O43482	P21549
PDB IDs			1H0C 1J04 2YOB 3R9A 4CBR 4CBS 4I8A 4KXK 4KYO 5F9S 5HHY 5LUC 5OFY 5OG0 6RV0 6RV1
Enriched GO Terms of Interacting Partners?
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