TMC6 and ZBTB2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMC6	ZBTB2
Description		transmembrane channel like 6	zinc finger and BTB domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Nuclear Membrane Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane	Nucleoplasm
	Molecular Function	Protein Binding Mechanosensitive Ion Channel Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Biological_process Ion Transmembrane Transport	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Glycated hemoglobin levels ( 34059833 31213470 28887542 29170429) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin A1c levels ( 29403010) Hemoglobin levels ( 32327693) hemolysis of donated blood (cold-storage) ( 34014839) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin ( 29403010 32888494 27863252) Mean corpuscular volume ( 29403010 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494 27863252) Red blood cell count ( 29403010 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Serum uric acid levels ( 29559957)	Chronic myeloid leukemia ( 21540461) Monocyte count ( 32888494) Refractive error ( 32231278)
Interacting Genes		3 interacting genes: CCR9 ZBTB2 ZDHHC17	29 interacting genes: ARID1B CREBBP DAXX GABARAPL2 IP6K2 KAT5 LHX4 LNX1 MEOX2 MKLN1 MOS MRPL11 PICK1 PIN1 RASSF8 SP1 STAT6 SUMO1 SUMO2 SUV39H1 TENT5B TMC6 TP53 UBE2I ZBTB18 ZBTB25 ZBTB49 ZMYND19 ZNF639
Entrez ID		11322	57621
HPRD ID		08386	10314
Ensembl ID		ENSG00000141524	ENSG00000181472
Uniprot IDs		A0A024R8V2 Q7Z403	Q8N680
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?