SAAL1 and PRRX1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SAAL1	PRRX1
Description		serum amyloid A like 1	paired related homeobox 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Chromatin Nucleus Nucleoplasm Cytosol
	Molecular Function	Molecular_function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding HMG Box Domain Binding
	Biological Process	Positive Regulation Of Synoviocyte Proliferation	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Mesenchymal Cell Proliferation Regulation Of Transcription By RNA Polymerase II Embryonic Limb Morphogenesis Inner Ear Morphogenesis Middle Ear Morphogenesis Positive Regulation Of Smoothened Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Neuron Fate Determination Embryonic Cranial Skeleton Morphogenesis Artery Morphogenesis Cartilage Development Roof Of Mouth Development Regulation Of Neuron Projection Regeneration Neuronal Stem Cell Population Maintenance Positive Regulation Of DNA Repair By Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS			Atrial fibrillation ( 28416818 28416822 29290336 29892015 22544366) Blood protein levels ( 29875488) Body shape index ( 34021172) Calcific aortic valve stenosis ( 32141789) Central corneal thickness ( 32528159) Early onset atrial fibrillation ( 28460022) Emphysema imaging phenotypes ( 26030696) Estimated glomerular filtration rate ( 31152163) Heel bone mineral density ( 30598549 28869591) Height ( 31562340) Hip circumference adjusted for BMI ( 28552196 34021172 25673412) Hip index ( 34021172) Intraocular pressure ( 29617998) Ischemic stroke (cardioembolic) ( 29531354) Macular thickness ( 30535121) Male-pattern baldness ( 29146897 28196072) PR interval ( 32439900) Prevalent atrial fibrillation ( 28416818) Refractive error ( 32231278) Response to angiotensin II receptor blocker therapy ( 22566498) Systemic lupus erythematosus ( 33536424) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		20 interacting genes: AMOTL2 C1orf87 DMAP1 MARK3 MRGPRX3 NEDD4 OGT PRRX1 PTPN5 RPH3AL RPS6KC1 SNAPC1 SNW1 SSX7 TCP10L TSGA10IP UEVLD ZNF443 ZNF57 ZNF620	11 interacting genes: ATP1B1 CINP GTF2I MAFF MAFG QSOX1 SAAL1 SOX10 SRF SUOX TNFRSF4
Entrez ID		113174	5396
HPRD ID		13999	01337
Ensembl ID		ENSG00000166788	ENSG00000116132
Uniprot IDs		G1UCX3 Q96ER3	P54821
PDB IDs
Enriched GO Terms of Interacting Partners?
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