MED8 and MED30

Number of citations of the paper that reports this interaction (PubMedID 24981860)
22

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		MED8	MED30
Description		mediator complex subunit 8	mediator complex subunit 30
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mediator Complex Core Mediator Complex	Ubiquitin Ligase Complex Nucleus Nucleoplasm Mediator Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Coregulator Activity Protein Binding	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Nuclear Receptor Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Protein Ubiquitination	Protein Ubiquitination Stem Cell Population Maintenance Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Feeling worry ( 29500382) Schizophrenia ( 28991256) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Common carotid intima-media thickness ( 29206233) Common carotid intima-media thickness in HIV infection ( 29206233) Dimensional psychopathology (Arousal) ( 29496196) Facial attractiveness (female raters) ( 30946739) Fasting blood glucose ( 29212154) Kawasaki disease ( 22446961) Leprosy ( 27976721) Midgestational total 25-hydroxyvitamin D levels (fetal genetic effect) ( 32047095) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Urate levels in obese individuals ( 25811787) Vestibular neuritis ( 30079052)
Interacting Genes		32 interacting genes: APP ARRB2 CCNC CDK8 CTDP1 ELOC HSPB3 KRT40 MED1 MED11 MED12 MED17 MED19 MED20 MED22 MED25 MED26 MED27 MED28 MED30 MED31 MED6 MED7 MED9 PEX14 PHYHIP PNMA1 PRKAR1B SNTA1 THOC7 UBALD1 USP49	17 interacting genes: APP DOCK8 HGS IFT20 KRTAP10-9 MED17 MED22 MED27 MED28 MED4 MED8 MED9 MTA2 NAP1L2 NME7 PCBD2 SS18L1
Entrez ID		112950	90390
HPRD ID		06991	11631
Ensembl ID		ENSG00000159479	ENSG00000164758
Uniprot IDs		Q96G25	Q96HR3
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?