PMF1 and CEP126

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PMF1	CEP126
Description		polyamine modulated factor 1	centrosomal protein 126
Image			No pdb structure
GO Annotations	Cellular Component	MIS12/MIND Type Complex Kinetochore Nuclear MIS12/MIND Complex Nucleoplasm Transcription Regulator Complex Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle	Cytoplasm Centrosome Midbody Ciliary Base
	Molecular Function	Transcription Coactivator Activity Protein Binding Leucine Zipper Domain Binding	Protein Binding
	Biological Process	Transcription By RNA Polymerase II Cell Cycle Chromosome Segregation Positive Regulation Of Transcription, DNA-templated Cell Division	Mitotic Spindle Organization Cytoplasmic Microtubule Organization Cilium Assembly Non-motile Cilium Assembly
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 30604766) Intracerebral hemorrhage ( 24656865) Ischemic stroke ( 29531354) Ischemic stroke (small-vessel) ( 29531354) Longevity (age >99th survival percentile) ( 31413261) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Stroke ( 29531354) White matter hyperintensity burden ( 25663218)
Interacting Genes		24 interacting genes: BICD2 CEP126 COPS6 COPS7A COPS7B CRMP1 DSN1 EFHC1 FBXO28 GDF9 GIT1 HSP90AA1 KDM1A MED31 MESD MIS12 NFE2L2 PTN SHC3 SUGT1 TBC1D21 TCP10L TSNAX USHBP1	87 interacting genes: AIMP2 AKTIP ARIH2 ATP6V1F ATRX BMI1 BRD1 C11orf58 CDKN2B CRCT1 CSTF2 DGCR6 DISC1 DLEU1 DNM1 DUSP12 DUSP23 EIF2S2 EIF6 EPN1 FAM118B FEZ1 FGFR3 FXR1 GEMIN7 GET4 GIT1 GOLGB1 GPRASP2 GSTO1 HMOX2 HTT ING5 KAT5 KAT7 KIF15 KLHL20 LAMTOR5 LPL LRRC1 LUC7L2 MAD2L1BP MAPK9 MLH1 MRPS6 NAP1L5 NAT9 NPM3 NSF NUDT21 ODF2L OFD1 PBK PDCD5 PFDN1 PIK3R3 PMF1 POLD1 POLR2M PPP1CA PPP1CC PRKRA PTPRS RAB27A RAN RBM23 RETREG2 RGS2 RIF1 ROGDI RPA2 RUVBL1 SAT1 SNRPG SPDL1 STAU2 TFG TNFRSF14 TNFSF11 TOMM20 TTR TXNDC9 VIM YAE1 YWHAZ ZBED8 ZNF24
Entrez ID		11243	57562
HPRD ID		11441	17212
Ensembl ID		ENSG00000160783	ENSG00000110318
Uniprot IDs		Q6P1K2	Q9P2H0
PDB IDs		5LSJ 5LSK
Enriched GO Terms of Interacting Partners?
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