PDCD10 and STK24

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
HPRD (two hybrid)

		PDCD10	STK24
Description		programmed cell death 10	serine/threonine kinase 24
Image
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Extracellular Exosome FAR/SIN/STRIPAK Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Membrane Extracellular Exosome
	Molecular Function	Protein Binding Protein Kinase Binding Protein Homodimerization Activity Protein N-terminus Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Cadherin Binding Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Angiogenesis Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell Migration Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Rho Protein Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Response To Hydrogen Peroxide Negative Regulation Of Apoptotic Process Stress Fiber Assembly Positive Regulation Of MAP Kinase Activity Wound Healing, Spreading Of Cells Positive Regulation Of Notch Signaling Pathway Protein Stabilization Establishment Of Golgi Localization Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Golgi Reassembly Positive Regulation Of Intracellular Protein Transport Regulation Of Golgi Organization Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Cellular Response To Leukemia Inhibitory Factor	Protein Phosphorylation Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Cellular Response To Starvation Negative Regulation Of Cell Migration Response To Hydrogen Peroxide Protein Autophosphorylation Regulation Of Axon Regeneration Execution Phase Of Apoptosis
Pathways			Apoptotic cleavage of cellular proteins Apoptotic execution phase
Drugs			Fostamatinib
Diseases
GWAS		Fast beta electroencephalogram ( 28070124) Platelet count ( 32888494)	Adult body size ( 32376654) Adventurousness ( 30643258) Alzheimer's disease ( 22159054) Educational attainment ( 25201988 23722424) Gastroesophageal reflux disease ( 34187846) General factor of neuroticism ( 30867560) General risk tolerance (MTAG) ( 30643258) Household income (MTAG) ( 31844048) Longevity ( 20834067) Methadone dose in opioid dependence ( 28115739) Mood instability ( 31168069) Reading disability or specific language impairment (pleiotropy) ( 25065397) Shoulder impingement or rotator cuff tear ( 33482370) Triglyceride levels ( 32203549) Urinary sodium excretion ( 31409800)
Interacting Genes		13 interacting genes: C4orf19 CHMP5 FAM118B FARSA FRYL MINAR1 PLEKHS1 PROSER2 RHOA STK24 STK25 STK26 STRN	12 interacting genes: CAB39 CASP3 CASP7 CASP8 ERBB2 LRRK2 NEDD4 OGT PDCD10 STK11 STK38L VAV2
Entrez ID		11235	8428
HPRD ID		10141	10385
Ensembl ID		ENSG00000114209	ENSG00000102572
Uniprot IDs		C9J363 Q9BUL8	B4DR80 Q5U0E6 Q6P0Y1 Q9Y6E0
PDB IDs		3AJM 3L8I 3L8J 3RQE 3RQF 3RQG 3W8H 3W8I 4GEH 4TVQ	3A7F 3A7G 3A7H 3A7I 3A7J 3CKW 3CKX 3ZHP 4O27 4QML 4QMM 4QMN 4QMO 4QMP 4QMQ 4QMS 4QMT 4QMU 4QMV 4QMW 4QMX 4QMY 4QMZ 4QNA 4QO9 4U8Z 4W8D 4W8E 7B30 7B31 7B32 7B33 7B34 7B35
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?