PSIP1 and SRSF1

Number of citations of the paper that reports this interaction (PubMedID 9885563)
50

Data Source:
HPRD (in vivo, in vitro)

		PSIP1	SRSF1
Description		PC4 and SFRS1 interacting protein 1	serine and arginine rich splicing factor 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Transcriptionally Active Chromatin	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Catalytic Step 2 Spliceosome
	Molecular Function	Double-stranded DNA Binding Transcription Coregulator Activity RNA Binding Protein Binding Supercoiled DNA Binding	RNA Binding MRNA Binding Protein Binding Protein Kinase B Binding DNA Topoisomerase Binding
	Biological Process	MRNA 5'-splice Site Recognition Regulation Of Transcription By RNA Polymerase II Response To Oxidative Stress Response To Heat	Alternative MRNA Splicing, Via Spliceosome MRNA 5'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Processing Positive Regulation Of RNA Splicing Oligodendrocyte Differentiation MRNA Transport Liver Regeneration
Pathways		Integration of provirus 2-LTR circle formation Integration of viral DNA into host genomic DNA Autointegration results in viral DNA circles APOBEC3G mediated resistance to HIV-1 infection Vpr-mediated nuclear import of PICs	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs			Copper
Diseases
GWAS			Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		14 interacting genes: CASP3 CASP7 CDC42 CSNK2A1 HCFC1 HMGA1 HMGA2 MAPK6 MTDH OGT SP1 SRSF1 SUB1 SUMO1	42 interacting genes: AKAP17A APP BCL10 C1QBP CACNA1A CD8A CDC42 CDK12 CDK6 CLK1 DANCR DIDO1 DYRK1A GEMIN2 HIPK3 HNRNPA0 LNX1 LUC7L3 NFYA NXF1 PPARG PRPF4 PRPF4B PSIP1 RNPS1 SCAF11 SNRNP70 SREK1 SRPK1 SRPK2 SRSF10 SRSF11 SRSF5 TCERG1 TNPO3 TOP1 TP53 U2AF1 U2AF2 XBP1 YTHDC1 ZRSR2
Entrez ID		11168	6426
HPRD ID		04688	02887
Ensembl ID		ENSG00000164985	ENSG00000136450
Uniprot IDs		O75475	Q07955 Q59FA2
PDB IDs		1Z9E 2B4J 2M16 2MSR 2MTN 2N3A 3F9K 3HPG 3HPH 3U88 3ZEH 4FU6 5N88 5OYM 5YI9 6EMO 6EMP 6EMQ 6EMR 6S01 6TRJ 6TVM 6Z2Y	1X4A 2M7S 2M8D 2O3D 3BEG 4C0O 6HPJ 7ABG
Enriched GO Terms of Interacting Partners?
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