CHGA and SCG3

Number of citations of the paper that reports this interaction (PubMedID 12388744)
30

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		CHGA	SCG3
Description		chromogranin A	secretogranin III
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Transport Vesicle Secretory Granule Chromaffin Granule Perinuclear Region Of Cytoplasm Neuronal Dense Core Vesicle	Extracellular Region Endoplasmic Reticulum Lumen Transport Vesicle Membrane Secretory Granule Membrane Secretory Granule Lumen
	Molecular Function		RNA Binding Protein Binding
	Biological Process	Regulation Of The Force Of Heart Contraction Mast Cell Chemotaxis Organelle Organization Regulation Of Blood Pressure Killing Of Cells Of Other Organism Protein Localization To Secretory Granule Negative Regulation Of Catecholamine Secretion Defense Response To Bacterium Mast Cell Degranulation Innate Immune Response Mast Cell Activation Negative Regulation Of Insulin Secretion Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Defense Response To Fungus Positive Regulation Of Cardiac Muscle Contraction Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Cardiac Muscle Relaxation Positive Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Neuron Death Positive Regulation Of Relaxation Of Cardiac Muscle Positive Regulation Of Dense Core Granule Biogenesis	Protein Localization To Secretory Granule
Pathways		Antimicrobial peptides	Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Body mass index ( 26426971)	Asthma ( 20159242) Blood protein levels ( 30072576 29875488) Intelligence (MTAG) ( 29326435) Mean reticulocyte volume ( 32888494)
Interacting Genes		6 interacting genes: CDC37 NEK2 PFDN1 PLG SCG3 UBC	4 interacting genes: CHGA DNM1L SDCBP TCF12
Entrez ID		1113	29106
HPRD ID		07170	11538
Ensembl ID		ENSG00000100604	ENSG00000104112
Uniprot IDs		G5E968 P10645 Q86T07	Q8WXD2
PDB IDs		1LV4 6R2X
Enriched GO Terms of Interacting Partners?
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