CD160 and HTR6

		CD160	HTR6
Description		CD160 molecule	5-hydroxytryptamine receptor 6
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Anchored Component Of Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane Cilium Dendrite Synapse
	Molecular Function	Signaling Receptor Binding Protein Binding Kinase Binding MHC Class I Protein Complex Binding MHC Class I Receptor Activity MHC Class Ib Receptor Activity Activating MHC Class I Receptor Activity	Histamine Receptor Activity G Protein-coupled Serotonin Receptor Activity Protein Binding Neurotransmitter Receptor Activity
	Biological Process	Angiogenesis Adaptive Immune Response Mucosal Immune Response Positive Regulation Of Natural Killer Cell Cytokine Production Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Angiogenesis T Cell Costimulation Positive Regulation Of Interferon-gamma Production Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Defense Response To Gram-negative Bacterium Negative Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of CD4-positive, Alpha-beta T Cell Costimulation Negative Regulation Of Adaptive Immune Memory Response Positive Regulation Of Endothelial Cell Apoptotic Process	G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Cerebral Cortex Cell Migration Positive Regulation Of TOR Signaling G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Serotonin receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs			Ziprasidone Amitriptyline Olanzapine Clozapine Loxapine Imipramine Chlorpromazine Haloperidol Amoxapine Paroxetine Cyclobenzaprine Ergoloid mesylate Doxepin Quetiapine Aripiprazole Chlorprothixene Dimethyltryptamine Lysergic acid diethylamide Iloperidone SGS518 PRX-07034 SUVN-502 Sertindole Mianserin Asenapine Zotepine Setiptiline Dihydroergocornine Gilteritinib Tiapride Dihydroergocristine Aripiprazole lauroxil
Diseases
GWAS		Diastolic blood pressure ( 30224653)	Chronotype ( 26955885 27494321) Morning person ( 30696823) Morning vs. evening chronotype ( 26955885 27494321)
Interacting Genes		13 interacting genes: AGTRAP CMTM5 CMTM6 GPR89B HTR6 MAL2 MDM4 NUP205 RNF115 SEC22B SYP THRA TNFRSF14	32 interacting genes: ABCA2 ACTB AIP AKR1A1 AP2M1 AP4S1 ATXN10 CD160 CHN1 CMSS1 COPS5 DDRGK1 DHRS1 EIF4A3 FYN GNAQ GNAS HDGFL2 IDS MAP1B NF1 NRXN3 PARP8 RUNDC3A SCHIP1 SLC6A1 SRRT SYT5 THY1 TMEM98 TTYH1 UQCRFS1
Entrez ID		11126	3362
HPRD ID		06833	03066
Ensembl ID		ENSG00000117281	ENSG00000158748
Uniprot IDs		O95971 Q6FH89	P50406
PDB IDs		6NG3 6NG9 6NGG
Enriched GO Terms of Interacting Partners?
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