DUSP14 and LMTK2

Number of citations of the paper that reports this interaction (PubMedID 28065597)
37

Data Source:
BioGRID (two hybrid)

		DUSP14	LMTK2
Description		dual specificity phosphatase 14	lemur tyrosine kinase 2
Image			No pdb structure
GO Annotations	Cellular Component		Early Endosome Golgi Apparatus Cytosol Integral Component Of Plasma Membrane Integral Component Of Membrane Growth Cone Neuronal Cell Body Receptor Complex Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	RNA Binding Protein Tyrosine Phosphatase Activity Protein Binding MAP Kinase Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Protein Serine/threonine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Phosphatase Inhibitor Activity Protein Binding ATP Binding Myosin VI Binding Protein Serine Kinase Activity
	Biological Process	Peptidyl-tyrosine Dephosphorylation	Receptor Recycling Protein Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Axonogenesis Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Endocytic Recycling Transferrin Transport Positive Regulation Of Kinase Activity Negative Regulation Of Catalytic Activity Early Endosome To Late Endosome Transport Protein Autophosphorylation
Pathways
Drugs
Diseases
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Monocyte count ( 32888494 27863252) Ovarian cancer ( 23535730) Platelet count ( 32888494 27863252) Plateletcrit ( 27863252) Red blood cell count ( 32888494)	Gamma glutamyl transferase levels ( 29403010 33339817) Hemoglobin levels ( 32327693) Prostate cancer ( 18264097) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408)
Interacting Genes		17 interacting genes: AATK CBY2 CD28 EPHA1 EPHA2 ERBB2 ERBB3 ERBB4 FGFR2 IGF1R ISYNA1 LMTK2 PRMT5 PTK7 ROR1 ROR2 UCHL5	24 interacting genes: CDC14A CDC25C CDK5 CDK5R1 DUSP14 DUSP19 DUSP29 DUSP6 ILKAP MTMR6 PPM1A PPM1F PPM1K PPP1CA PPP1CB PPP1CC PPP1R2 PPP3CB PTPDC1 PTPN12 PTPN6 PTPRR STYX TPTE2
Entrez ID		11072	22853
HPRD ID		09427	13994
Ensembl ID		ENSG00000276023	ENSG00000164715
Uniprot IDs		O95147 Q6FI36	Q8IWU2
PDB IDs		2WGP
Enriched GO Terms of Interacting Partners?
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