RAPGEF4 and ZC3H11A

Number of citations of the paper that reports this interaction (PubMedID 24722188)
63

Data Source:
BioGRID (two hybrid)

		RAPGEF4	ZC3H11A
Description		Rap guanine nucleotide exchange factor 4	zinc finger CCCH-type containing 11A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane Hippocampal Mossy Fiber To CA3 Synapse	Nucleoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding CAMP Binding Small GTPase Binding	RNA Binding MRNA Binding Protein Binding Metal Ion Binding
	Biological Process	Adaptive Immune Response G Protein-coupled Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Calcium-ion Regulated Exocytosis Regulation Of Exocytosis CAMP-mediated Signaling Insulin Secretion Regulation Of Catalytic Activity Regulation Of Synaptic Vesicle Cycle	Poly(A)+ MRNA Export From Nucleus
Pathways		Integrin signaling Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Rap1 signalling Regulation of insulin secretion	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Fasting blood glucose ( 33842983) Fasting plasma glucose ( 25187374) GLP-1 levels in response to oral glucose tolerance test (fasting) ( 29093273) HDL cholesterol levels ( 32203549) Hippocampal volume ( 25625606) Lateral ventricle temporal horn volume ( 31530798)	Breast cancer ( 25038754) Male-pattern baldness ( 28196072)
Interacting Genes		13 interacting genes: ATXN1 BMERB1 DEF6 LRRK2 MAP1A RAP1A RAP2A RIMS2 RRAS2 SWAP70 TRAF2 TSPOAP1 ZC3H11A	9 interacting genes: MIR141 MIR214 MIR9-1 MIR9-2 MLH1 MTNR1A RAPGEF4 SMARCB1 SUMO2
Entrez ID		11069	9877
HPRD ID		06929	11100
Ensembl ID		ENSG00000091428	ENSG00000058673
Uniprot IDs		B7Z278 Q8WZA2	O75152
PDB IDs
Enriched GO Terms of Interacting Partners?
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