CHD1 and SRSF3

Number of citations of the paper that reports this interaction (PubMedID 12890497)
24

Data Source:
HPRD (two hybrid, in vitro)

		CHD1	SRSF3
Description		chromodomain helicase DNA binding protein 1	serine and arginine rich splicing factor 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	DNA Binding DNA Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity Methylated Histone Binding ATP-dependent Chromatin Remodeler Activity	RNA Binding Protein Binding Phospholipase Binding Sequence-specific MRNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II DNA Duplex Unwinding Positive Regulation By Host Of Viral Transcription	MRNA Splicing, Via Spliceosome MRNA Export From Nucleus Regulation Of MRNA Splicing, Via Spliceosome Cellular Response To Leukemia Inhibitory Factor
Pathways		Estrogen-dependent gene expression	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Basophil percentage of white cells ( 27863252) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Neutrophil percentage of granulocytes ( 27863252) Periodontitis (Mean PAL) ( 24024966) Renal sinus fat ( 22044751)	Glaucoma (primary open-angle) ( 33627673) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		10 interacting genes: BCLAF1 FER H3-3A H3-4 HDAC1 NCOR1 SAFB SPP1 SRSF3 SSRP1	40 interacting genes: - APP CHD1 CIRBP CLK1 CLK2 CLK3 CNNM3 DUX4 EXOSC6 GEMIN2 HMGB1 HNRNPK IL7R LNX1 NXF1 PCBP1 PCBP2 PCBP3 PCDHB14 PRPF31 RBM3 RBM7 RBMX RBMY1A1 RNPS1 RPL9 SCAF11 SDCBP SREK1 SRPK1 SRPK2 SRSF2 SRSF8 TRA2B U2AF1 U2AF2 YWHAB YWHAG YWHAQ
Entrez ID		1105	6428
HPRD ID		03668	04530
Ensembl ID		ENSG00000153922	ENSG00000112081
Uniprot IDs		B3KT33 O14646	B2R6F3 P84103
PDB IDs		2B2T 2B2U 2B2V 2B2W 2B2Y 2N39 4B4C 4NW2 4O42 5AFW	2I2Y 2I38
Enriched GO Terms of Interacting Partners?
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